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P1054 : MYLOX-1: AN OPEN-LABEL, PHASE IIA STUDY OF THE SAFETY, TOLERABILITY, PHARMACOKINETICS AND PHARMACODYNAMICS OF ORAL LOXL2 INHIBITOR, GB2064, IN MYELOFIBROSIS

Researchers

Presenter

  • Claire Harrison

Principal Investigators

  • John Mascarenhas

  • Raajit Rampal

  • Daniela Cilloni

  • Bertil Lindmark

  • Bhupinder Singh

  • Brian Jacoby

  • Srdan Verstovsek

Medical Centers

  • University Hospital San Luigi Gonzaga,Orbassano,Italie

  • Icahn School of Me

  • MD Anderson Cancer Center,Houston, TX,Estados Unidos

  • Guy's and St Thomas' Hospital,London,Royaume-uni

  • Memorial Sloan Kettering Cancer Center,New York,Vereinigte Staaten

  • Guy's and St Thomas' Hospital,London,Reino Unido

  • Galecto Inc,Copenhagen,Dänemark

  • Icahn School of Medicine at Mount Sinai,New York,Verenigde Staten

  • Galecto Inc,Copenhagen,Dänemark

  • University Hospital San Luigi Gonzaga,Orbassano,Italie

  • Memorial Sloan Kettering,New York, NY,Estados Unidos

  • Memorial Sloan Kettering Cancer Center,New York,Vereinigte Staaten

  • Galecto Inc,Copenhagen,Dänemark

  • University Hospital San Luigi Gonzaga,Orbassano,Italie

  • Memorial Sloan Kettering,New York, NY,Estados Unidos

  • Galecto Inc,Copenhagen,Dänemark

  • MD Anderson...

  • Guy's and St Thomas' Hospital,London,Reino Unido

  • MD Anderson Cancer Center ,Houston,Verenigde Staten

  • Gu-s and St Thoma- NHS, London, United Kingdom

  • Icahn School of Medicine at Mount Sinai, New York, NY

  • Icahn School of Medicine at Mount Sinai,New York,Estados Unidos

  • Memorial Slo

  • University Hospital San Luigi Gonzaga, Cardiology, Orbassano, Italy

  • Memorial Sloan Kettering Cancer Center,New York ,États-unis

  • Memorial Sloan-Kettering Cancer Center, New York, NY, United States

  • Galecto Inc,Copenhagen,Dänemark

  • Galecto Inc,Copenhagen,Dänemark

  • Icahn School of Medicine at Mount Sinai, New York, NY

  • Icahn School of Medicine at Mount Sinai, New York, New York, United States

  • Guy's and St Thomas Hospital,London,Соедин

  • University Hosp

  • Icahn School of Medicine at Mount Sinai, New York, New York, United States

  • University of Texas MD Anderson Cancer Center, Houston, Texas, United States

  • Guy's and St Thomas' Hospital,London,Vereinigtes Königreich

  • MD Anderson Cancer Center,Houston, TX,Estados Unidos

  • University Hospital San Luigi Gonzaga,Orbassano,Italie

  • MD Anderson Cancer Center,Houston, TX,Estados Unidos

  • MD Anderson Cancer Center ,Houston,Verenigde Staten

  • Guy's and St Thomas' Hospital,London,Vereinigtes Königreich

  • Galecto Inc,Copenhagen,Дания

  • University Hospital San Luigi Gonzaga,Orbassano,Italie

Locations

  • United Kingdom

  • United States

  • Italy

  • Denmark

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Myelofibrosis

  • Myeloid neoplasms

  • Solid malignancies

Biomarkers

  • Platelet derived growth factor

  • Connective tissue growth factor

  • Chitinase 3 Like 1

  • Plasminogen activator ihnibitor-1

  • Janus kinase

Drug/Treatment

  • Becaplermin

Outcome

  • N/A

Study Design

  • Pharmacokinetics

  • Pharmacodynamics

  • Open Label

Phase

  • II

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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