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P791 : COMMON VARIANTS IN COMPLEMENT PROTEINS, C3 AND CR1, ENHANCE COMPLEMENT ATTACK ON PNH ERYTHROCYTES AND INCREASE RISK FOR EXTRAVASCULAR HAEMOLYSIS

Researchers

Presenter

  • April Joy Baral

Principal Investigators

  • Claire Mckinley

  • Rosie Fellows

  • Thomas Hallam

  • Thomas Cox

  • Daniel Payne

  • Stephen Richards

  • Alexandra Pike

  • Richard Kelly

  • Morag Griffin

  • Peter Hillmen

  • Kevin Marchbank

  • David Kavanagh

  • Darren Newton

  • Claire Harris

Medical Centers

  • Department of Haematology ,St James University Hospital,Leeds,Vereinigtes Königreich

  • Haematological Malignancy Diagnostic Service, St. James's University Hospital, Leeds, United Kingdom

  • Translational and Clinical Research Institute,Newcastle University,Newcastle upon Tyne,Regno Unito

  • Translational and Clinical Research Institute,Newcastle University,Newcastle upon Tyne,Regno Unito

  • Division of Haematology and Immunology, Leeds Institute of Medical Research ,University of Leeds,Leeds,Royaume-uni

  • Department of Haematology ,St James University Hospital,Leeds,Vereinigtes Königreich

  • Haematological Malignancy Diagnostic Service, St. James's University Hospital, Leeds, United Kingdom

  • Division of Haematology and Immunology, Leeds Institute of Medical Research ,University of Leeds,Leeds,Royaume-uni

  • Translational and Clinical Research Institute,Newcastle University,Newcastle upon Tyne,Regno Unito

  • Translational and Clinical Research Institute,Newcastle University,Newcastle upon Tyne,Regno Unito

  • Department of Haematology,St James University Hospital,Leeds,Royaume-uni

  • Translational and Clinical Research Institute,Newcastle University,Newcastle upon Tyne,Regno Unito

  • Division of Haematology and Immunology,Leeds In

  • Department of Haematology,St James University Hospital,Leeds,Royaume-uni

  • Division of Haematology and Immunology, Leeds Institute of Medical Research ,University of Leeds,Leeds,Royaume-uni

  • Translational and Clinical Research Institute,Newcastle University,Newcastle upon Tyne,Regno Unito

  • Translational and Clinical Research Institute,Newcastle University,Newcastle upon Tyne,Regno Unito

  • Translational and Clinical Research Institute,Newcastle University,Newcastle upon Tyne,Regno Unito

  • Division of Haematology and Immunology, Leeds Institute of Medical Research ,University of Leeds,Leeds,Royaume-uni

  • Translational and Clinical Research Institute,Newcastle University,Newcastle upon Tyne,Regno Unito

  • Haematological Malignancy Diagnostic Service, St. James's University Hospital, Leeds, United Kingdom

  • Translational and Clinical Research Institute,Newcastle University,Newcastle upon Tyne,Regno Unito

  • Hemat

  • Department of Hematology,

  • Haematological Malignancy Diagnostic Service, St. James's University Hospital, Leeds, United Kingdom

  • Division of Bacteriology and Immunology,

  • Division of Haematology and Immunology, Leeds Institute of Medical Research ,University of Leeds,Leeds,Royaume-uni

  • Division of Haematology and Immunology, Leeds Institute of Medical Research ,University of Leeds,Leeds,Royaume-uni

  • Translational and Clinical Research Institute,Newcastle University,Newcastle upon Tyne,Regno Unito

  • Translational and Clinical Research Institute,Newcastle University,Newcastle upon Tyne,Regno Unito

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • N/A

Disease

  • N/A

Biomarkers

  • Lactate

  • Lactate dehydrogenase

Drug/Treatment

  • Eculizumab

Outcome

  • N/A

Study Design

  • N/A

Phase

  • N/A

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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