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P1189 : INITIAL SAFETY RUN-IN RESULTS OF THE PHASE III POLARGO TRIAL: POLATUZUMAB VEDOTIN PLUS RITUXIMAB, GEMCITABINE, AND OXALIPLATIN IN PATIENTS WITH RELAPSED/REFRACTORY DIFFUSE LARGE B-CELL LYMPHOMA

Researchers

Presenter

  • Andrew McMillan

Principal Investigators

  • Corinne Haioun

  • Juan-Manuel Sancho

  • Andreas Viardot

  • Antonia Rodriguez Izquierdo

  • Eva Maria Donato Martin

  • Alejandro Martn Garca-Sancho

  • Jose Sandoval-Sus

  • Herv Tilly

  • Elisabeth Vandenberghe

  • Jamie Hirata

  • Priya Choudhry

  • Yi Meng Chang

  • Lisa Musick

  • Matthew Matasar

Medical Centers

  • ICO-HU Germans Trias I Pujol,Barcelona,Spain

  • Genentech Inc., San Francisco, United States

  • Centre Henri Becquerel, University of Rouen, Rouen, France

  • Hospital Universitario 12 de Octubre Servicio de Hematología,Madrid,Spagna

  • Hoffmann-La Roche Ltd, Mississauga, ON, Canada

  • Genentech, Inc.,South San Francisco, CA,Stati Uniti

  • Hospital Universitario Dr Peset Servicio de Hematología,Valencia,España

  • Hospital Clínico Universitario de Salamanca Servicio de Hematología,Salamanca,Spanien

  • Memorial Sloan Kettering Cancer Center,New York ,États-unis

  • Genentech, Inc.,South San Francisco,Verenigde Staten

  • Hospital Clínico Universitario de Salamanca Servicio de Hematología,Salamanca,Spanien

  • ICO-HU Germans Trias I Pujol,Barcelona,España

  • University of Ulm, Ulm, Germany

  • Memorial Sloan Kettering Cancer Center,New York,Vereinigte Staaten

  • Hospital Universitario 12 de Octubre Servicio de Hematología,Madrid,Spagna

  • Hospital Universitario 12 de Octubre Servicio de Hematología,Madrid,Spagna

  • Centre Henri Becquerel, University of Rouen, Rouen, France

  • ICO-HU Germans Trias I Pujol,Barcelona,Spain

  • St James Hospital Cancer Clinical Trials Office,Dublin,Ierland

  • St James Hospital Cancer Clinical Trials Office,Dublin,Ierland

  • Hoffmann-La Roche Ltd, Mississauga, ON, Canada

  • Hospital Clínico Universitario de Salamanca Servicio de Hem

  • Hospital Univ 12 De Octubre, Servicio De Hematologia, Madrid, Spain

  • Lymphoïd Malignancies Unit, Groupe Hospitalier Henri Mondor, Créteil Cedex, France

  • Hospital Universitario y...

  • ICO-HU Germans Trias I Pujol,Barcelona,Испания

  • ICO-HU Germans Trias I Pujol,

  • Hoffmann-La Roche Ltd,Mississauga, ON,Канада

  • Hospital Universitario Dr Peset Servicio de Hematología,Valencia,España

  • Hospital Clínico Universitario de Salamanca Servicio de Hematología,Salamanca,Spanien

  • Centre Henri Becquerel, University of Rouen, Rouen, France

  • Department of Clinical Hematology,Nottingham University Hospitals NHS,Nottingham,Storbritannien

  • Lymphoïd Malignancies Unit, Groupe Hospitalier Henri Mondor, Créteil Cedex, France

  • Memorial Sloan Kettering Cancer Center,New York,Vereinigte Staaten

  • Hospital Universitario 12 de Octubre Servicio de Hematología,Madrid,Spagna

  • Lymphoïd Malignancies Unit, Groupe Hospitalier Henri Mondor, Créteil Cedex, France

  • St James Hospital Cancer Clinical Trials Office,Dublin,Ierland

  • Hospital Universitario Dr Peset Servici

  • Memorial Sloan Kettering Cancer Center, Port Washington, NY

  • Genentech, Inc.,South San Francisco,Verenigde Staten

  • Department of Clinical Hematology,Nottingham University Hospitals NHS,Nottingham,Storbritannien

  • Centre for Clinical Haematology, Nottingham University Hospital, Nottingham, United Kingdom

  • Memorial Sloan Kettering Cancer Center, Port Washington, NY

  • Centre Henri Becquerel and Univ

  • Department of Clinical Hematology,Nottingham University Hospitals NHS,Nottingham,Storbritannien

  • University Hospital of Ulm,Ulm,Германия

  • Hospital Universitario Dr Peset Servicio de Hematología,Valencia,España

  • St James Hospital Cancer Clinical Trials Office,Dublin,Ierland

  • Hoffmann-La Roche Ltd, Mississauga, ON, Canada

  • Lymphoïd Malignancies Unit, Groupe Hospitalier Henri Mondor, Créteil Cedex, France

  • Memorial Sloan-Kettering Cancer Center, New York, NY, United States

  • Centre Henri Becquerel, University of Rouen, Rouen, France

  • University of Ulm, Ulm, Germany

  • ICO-HU Germans Trias I Pujol,Barcelona,España

  • St James Hospital Cance

  • Hospital Universitario Dr Peset Servicio de Hematología,Valencia,España

  • St James Hospital Cancer Clinical Trials Office,Dublin,Ierland

  • Genentech, Inc.,South San Francisco, CA,Stati Uniti

  • ICO-HU Germans Trias I Pujol,Barcelona,Spain

  • ICO-HU Germans Trias I Pujol,Barcelona,Spain

  • Genentech Inc., San Francisco, United States

  • ICO-HU Germans Trias I Pujol,Barcelona,España

  • Memorial Sloan Kettering, NY

  • Hospital Clínico Universitario de Salamanca Servicio de Hematología,Salamanca,Spanien

  • Genentech, Inc.,South San Francisco, CA,Stati Uniti

  • Hospital Universitario Dr Peset Servicio de Hematología,Valencia,España

Locations

  • United Kingdom

  • France

  • Venezuela

  • Spain

  • Germany

  • Mexico

  • United States

  • Canada

  • Ireland

Companies

  • N/A

Study Components

Therapeutic Area

  • Peripheral Nervous System

  • Oncology (ONC)

Disease

  • Diffuse large B-cell lymphoma

  • Peripheral neuropathy

  • B cell lymphomas

  • Lymphomas

Biomarkers

  • Granulocyte colony-stimulating factor

Drug/Treatment

  • Filgrastim

  • Polatuzumab vedotin

  • Gemcitabine

  • Oxaliplatin

  • Rituximab

Outcome

  • N/A

Study Design

  • N/A

Phase

  • III

Study Id's

  • NCT04182204

Sponsors

  • N/A

Result

  • N/A

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