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P1460 : SAFETY AND EFFICACY FINDINGS OF AUTO1, A FAST-OFF RATE CD19 CAR, IN RELAPSED/REFRACTORY PRIMARY CNS LYMPHOMA

Researchers

Presenter

  • Claire Roddie

Principal Investigators

  • Maeve O'Reilly

  • Giulia Agliardi

  • John Garcia

  • Mark Lowdell

  • Alastair Hotblack

  • Helene Dreau

  • Maria Marzolini

  • Leigh Wood

  • Clemency Every-Clayton

  • Alka Lal

  • Yenting Ngai

  • Bilyana Popova

  • Aman Malhi

  • Victoria Spanswick

  • Helen Lowe

  • Leah Ensell

  • John Hartley

  • Lewis Thorne

  • Harpreet Hyare

  • Patrick Murphy

  • David Linch

  • Christopher Fox

  • Karl Peggs

  • Kate Cwynarski

  • Martin Pule

Medical Centers

  • RCTS,Kings College London,London,Verenigd Koninkrijk

  • Department of Medical Oncology, University College London Hospital, London, United Kingdom

  • Oxford Molecular Diagnostics Centre, University of Oxford, Oxford, United Kingdom

  • Research Department of Haematology,University College London,London,Regno Unito

  • Hematology,University College London Hospitals,London,Royaume-uni

  • Dept. Haematology,University College London Hospitals,London,Vereinigtes Königreich

  • UCL Cancer Trials Centre,University College London,London,Royaume-uni

  • University College London Hospitals,London,Royaume-uni

  • Kings College London, London, United Kingdom

  • UCL Cancer Institute, University College London,, London, United Kingdom

  • King's College London,London,Reino Unido

  • Dept. Neurosurgery,National Hospital for Neurology and Neurosurgery, Queen's Square, ,London,Royaume-uni

  • Department of Clinical Hematology,Nottingham University Hospitals NHS,Nottingham,Storbritannien

  • Oxford Molecular Diagnostics Centre,University of Oxford,Oxford,Vereinigtes Königreich

  • Cancer Trials Centre, University College London, London, United Kingdom

  • Department of Haematological Medicine, King's College London, London, United Kingdom

  • Research Department of Haematology,University College London,London,Regno Unito

  • Dept. Haematology,University College London Hospitals,London,Vereinigtes Königreich

  • UCL Cancer Institute,University College London,London,Ve

  • Research Department of Haemato

  • Dept. Imaging,University College London Hospitals,London,Regno Unito

  • UCL Cancer Institute, University College London,, London, United Kingdom

  • UCL Cancer Institute,University College London,London,Royaume-uni

  • Dept. Neurosurgery,National Hospital for Neurology and Neurosurgery, Queen's Square, ,London,Royaume-uni

  • Oxford Molecular Diagnostics Centre,University of Oxford,Oxford,Royaume-uni

  • University College London Hospitals,London,Vereinigtes Königreich

  • Department of Haematology, Nottingham City Hospital, Nottingham, United Kingdom

  • Dept. Neurosurgery,National Hospital for Neurology and Neurosurgery, Queen's Square, ,London,Royaume-uni

  • RCTS,Kings College London,London,Соединённое Королевство

  • Dept. Imaging,University College London Hospitals,London,Regno Unito

  • King's College London,London,Royaume-uni

  • RCTS,K

  • Cancer Clinial Trials Unit,University College London,London,Vereinigtes Königreich

  • Medicine,King's College London,London,Vereinigtes Königreich

  • Dept. Neurosurgery,National Hospital for Neurology and Neurosurgery, Queen's Square, ,London,Royaume-uni

  • Dept. Neurosurgery,National Hospital for Neurology and Neurosurgery, Queen's Square, ,London,Royaume-uni

  • Department of Clinical Hematology,Nottingham University Hospitals NHS,Nottingham,Storbritannien

  • UCL Cancer Trials Centre,University College London,London,Royaume-uni

  • Oxford Molecular Diagnostics Centre, University of Oxford, Oxford, United Kingdom

  • Oxford Molecular Diagnostics Centre, University of Oxford, Oxford, United Kingdom

  • Dept. Haematology,Universi

  • Dept. Clinical Psychology,National Hospital for Neurology a

  • Oxford

  • Dept. Neurosurgery,National Hospital for Neurology and Neurosurgery, Queen's Square, ,London,Royaume-uni

  • Dept. Neurosurgery,National Hospital for Neurology and Neurosurgery, Queen

  • Department of Clinical Hematology,Nottingham University Hospitals NHS,Nottingham,Storbritannien

  • Dept. Neuroimaging,Un

  • King's College London,London,Reino Unido

  • Dept. Imaging,University College London Hospitals,London,Regno Unito

  • UCL Cancer Trials Centre,University College London,London,Royaume-uni

  • Hematology,University College London Hospitals,London,Royaume-uni

  • UCL Cancer Institute, University College London,, London, United Kingdom

  • Dept. Imaging,University College London Hospitals,London,United Kingdom

  • Dept. Neuroimaging,University College London Hospital,London,Reino Unido

  • Cancer Clinial Trials Unit,University College London,London,Vereinigtes Königreich

  • UCL Cancer Trials Centre,University

Locations

  • United Kingdom

  • United States

  • India

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Primary central nervous system lymphoma

Biomarkers

  • Cluster of Differentiation 19

  • Cerebrospinal fluid

Drug/Treatment

  • Cyclophosphamide

  • Cyclophosphamide Injection

  • Pembrolizumab

  • fludarabine tablet

Outcome

  • N/A

Study Design

  • N/A

Phase

  • N/A

Study Id's

  • NCT04443829

Sponsors

  • N/A

Result

  • N/A

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