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S304 : SUTIMLIMAB, A COMPLEMENT C1S INHIBITOR, PROVIDES SUSTAINED IMPROVEMENTS IN PATIENT-REPORTED OUTCOMES IN PATIENTS WITH COLD AGGLUTININ DISEASE (CAD): 2 YEAR FOLLOW-UP FROM THE CARDINAL STUDY

Researchers

Presenter

  • Alexander Rth

Principal Investigators

  • Catherine M. Broome

  • Wilma Barcellini

  • Tor Henrik Anderson Tvedt

  • Yoshitaka Miyakawa

  • Shirley D'Sa

  • David Cella

  • Florence Joly

  • Jennifer Wang

  • Timothee Sourdille

  • Frank Shafer

  • Marek Wardecki

  • Ilene C. Weitz

Medical Centers

  • Section for Hematology, Department of Medicine, Haukeland University Hospital, Bergen, Norway

  • Sanofi, Chilly-Mazarin, France

  • Sanofi Bridgewater NJ United States

  • Sanofi, Cambridge, United States

  • Fondazione IRCCS Ca' Granda Ospedale Maggiore

  • Sanofi, Chilly-Mazarin, France

  • Section for Hematology, Departm

  • Department of Hematology and Stem Cell Transplantation, West German Cancer Center, Univers

  • Thrombosis and Hemostasis Center,Saitama Medical University Hospital,Saitama,Japan

  • Section for Hematology, Department of Medicine, Haukeland University Hospital, Bergen, Norway

  • Sanofi, Cambridge, MA

  • Section for Hematology, Department of Medicine, Haukeland University Hospital, Bergen, Norway

  • Sanofi,Chilly-Mazarin,Франция

  • Sanofi, Chilly-Mazarin, France

  • Section for Hematology, Department of Medicine, Haukeland University Hospital, Bergen, Norway

  • Depa

  • Sanofi, Bridgewater, NJ

  • Sanofi, Chilly-Mazarin, France

  • Sanofi,Cambridge, MA,Estados Unidos

  • IRCCS Ca Granda, Ospedale Maggiore Policlinico, Milano, Italy

  • Sanofi,Cambridge, MA,Vereinigte Staaten

  • Sanofi,Warsaw,Pologne

  • Thrombosis and Hemostasis Center,Saitama Medical University Hospital,Saitama,Japan

  • Sanofi, Chilly-Mazarin, France

  • Division of Hematology, MedStar Georgetown University Hospital,Washington DC,Vereinigte Staaten

  • Fondazione IRCCS Ca' Granda Ospedale Maggiore

  • Keck School of Medicine of USC, Los Angeles, CA

  • Clinic for Hematology and Stem Cell Transplantation, West German Cancer Center, University Hospital of Essen, University of Duisburg-Essen, Essen, Germany

  • Sanofi,Cambridge, MA,États-unis

  • UCLH Centre for Waldenström's Macroglobulinemia and Related Conditions, University College London Hospitals NHS Foundation Trust,London,Vereinigtes Königreich

  • Sanofi,Bridgewater,États-unis

  • Sanofi,Bridgewater, NJ,Estados Unidos

  • Sanofi,Bridgewater, NJ,Vereinigte Staaten

  • Department of Medical Social Sciences,Center for Patient-Centered Outcomes, Institute for Public Health and Medicine, Feinberg School of Medicine, Northwestern University,Chicago, IL,États-unis

  • Sanofi,Warsaw,Польша

  • Keck School of Medicine of USC, Los Angeles, CA

  • USC Keck School of Medicine, Los Angeles, United States

  • Sanofi,Cambridge, MA,Stati Uniti

  • UCLH Centre for Waldenström's Macroglobulinemia and Related Conditions, University College London Hospitals NHS Foundation Trust,London,Vereinigtes Königreich

  • Division of Hematology, MedStar Geor

  • Sanofi,Warsaw,Pologne

  • Keck School of Medicine of USC,Los Angeles, CA,Vereinigte Staaten

  • Sanofi,Warsaw,Pologne

  • Sanofi,Bridgewater, NJ,Stati Uniti

  • Keck School of Medicine of USC,Los Angeles, CA,Vereinigte Staaten

  • Keck School of Medicine of USC

  • UCLH Centre for Waldenström's Macroglobulinemia and Related Conditions, University College Lo

  • Division of Hematology, MedStar Georgetown University Hospital,Washington DC,Vereinigte Staaten

  • Fondazione IRCCS Ca' Granda Ospedale Maggiore

  • Division of Hematology, MedStar Georgetown University Hospital,Washington DC,Vereinigte Staaten

  • Thrombosis and Hemostasis Center, Saitama Medical University

  • Department of Medical Social Sciences,Center for Patient-Centered Outcomes, Institute for Public Health and Medicine, Feinberg School of Medicine, Northwestern University,Chicago, IL,États-unis

  • Keck School of Medicine of USC,Los Angeles, CA,Estados Unidos

  • Sanofi,Chilly-Mazarin,Frankrijk

  • Sanofi,Cambridge, MA,Vereinigte Staaten

  • Fondazione IRCCS Ca' Granda Ospedale Maggiore

  • Division of Hematology, MedStar Georgetown University Hospital,Washington DC,Vereinigte Staaten

  • Sanofi,Warsaw,Pologne

  • Thrombosis and Hemostasis Center,Saitama Medical University Hospital,Saitama,Japan

  • Clinic for Hematology and Stem Cell Transplantation, West German Cancer Center, University Hospital of Essen, University of Duisburg-Essen, Essen, Germany

  • Sanofi,Bridgewater, NJ,Vereinigte Staaten

Locations

  • Germany

  • United States

  • Italy

  • Norway

  • Japan

  • United Kingdom

  • France

  • Poland

Companies

  • N/A

Study Components

Therapeutic Area

  • Pulmonary/Respiratory Diseases

Disease

  • Chronic obstructive pulmonary disease

Biomarkers

  • Complement Component 1, S Subcomponent

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • Open Label

  • Single Arm

Phase

  • III

Study Id's

  • NCT03347396

Sponsors

  • N/A

Result

  • N/A

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