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P1214 : SUBCUTANEOUS EPCORITAMAB + R-CHOP FOR FIRST-LINE TREATMENT OF PATIENTS WITH HIGH-RISK DIFFUSE LARGE B-CELL LYMPHOMA: PHASE 1/2 UPDATE

Researchers

Presenter

  • Michael Roost Clausen

Principal Investigators

  • Fritz Offner

  • David Belada

  • Joshua Brody

  • Yasmin Karimi

  • Raul Cordoba

  • Sylvia Snauwaert

  • Liwei Wang

  • Jun Wu

  • Brian Elliott

  • Lorenzo Falchi

Medical Centers

  • University of Michigan Comprehensive Cancer Center, Ann Arbor, MI

  • Icahn School of Me

  • AbbVie Inc ,North Chicago, IL,États-unis

  • Universitair Ziekenhuis Gent, Ghent, Belgium

  • The Christie NHS Foundation Trust and Manchester Cancer Research Centre,Manchester,Regno Unito

  • Department of Hematology,AZ Sint-Jan Hospital,Bruges,Belgique

  • Genmab,Princeton,États-unis

  • Genmab,Princeton,Estados Unidos

  • Department of Hematology,AZ Sint-Jan Hospital,Bruges,Belgique

  • Lymphoma Service,Memorial Sloan Kettering Cancer Center,New York,Stati Uniti

  • The Christie NHS Foundation Trust and Manchester Cancer Research Centre,Manchester,Regno Unito

  • Vejle Hospital, Vejle, Denmark

  • Department of Hematology,AZ Sint-Ja

  • AbbVie Inc ,North Chicago, IL,Vereinigte Staaten

  • Fourth Department of Internal Medicine - Hematology, Charles University Hospital and Faculty of Medicine, Hradec Kralove, Czech Republic

  • AbbVie Inc ,North Chicago, IL,Stati Uniti

  • Genmab,Princeton,Vereinigte Staaten

  • Icahn School of Medicine at Mount Sinai,New York,Verenigde Staten

  • Universitair Ziekenhuis Gent, Ghent, Belgium

  • Vejle Hospital, Vejle, Denmark

  • Department of Hematology, AZ Sint-Jan AV, Brugge, Belgium

  • AbbVie, N Chicago, United States

  • Universitair Ziekenhuis Gent, Ghent, Belgium

  • University of Michigan Comprehensive Cancer Center, Ann Arbor, MI

  • Universitair Ziekenhuis Gent, Ghent, Belgium

  • Endocrinology Service, Memorial Sloan Kettering Cancer Center, New York, United States

  • Department of Hematology,AZ Sint-Jan Hospital,Bruges,Belgique

  • Genmab,Princeton,USA

  • The Christie NHS Foundation Trust and Manchester Cancer Research Centre,Manchester,Regno Unito

  • Genmab,Princeton, NJ,United States

  • Genmab,Princeton,Stati Uniti

  • Icahn School of Medicine at Mount Sinai, New York, NY

  • Icahn School of Medicine at Mount Sinai,New York,Estados Unidos

  • Fundacion Jimenez Diaz University Hospital, Health Research Institute IIS-FJD,Madrid,Spagna

  • Universitair Ziekenhuis Gent, Ghent, Belgium

  • Fundacion Jimenez Diaz University Hospital, Health Research Institute IIS-FJD,Madrid,Spagna

  • Lymphoma Service,Memorial Sloan Kettering Cancer Center,New York,Stati Uniti

  • Vejle Hospital, Vejle, Denmark

  • Lymp

  • Lymphoma Service,Memorial Sloan Kettering Cancer Center,New York,Stati Uniti

  • Vejle Hospital, Vejle, Denmark

  • Fundacion Jimenez Diaz Universi

  • Genmab,Princeton,Vereinigte Staaten

  • Memorial Sloan Kettering Cancer Center,New York ,États-unis

  • 2nd Department of Intern

  • The Ch

  • Fundacion Jimenez Diaz University Hospital, Health Research Institute IIS-FJD,Madrid,Spagna

  • Vejle Hospital, Vejle, Denmark

  • University of Michigan Comprehensive Cancer Center, Ann Arbor, MI

  • University of Michigan Comprehensive Cancer Center, Ann Arbor, MI

  • Icahn School of Medicine at Mount Sinai, New York, NY

  • Icahn School of Medicine at Mount Sinai, New York, New York, United States

  • The Christie NHS Foundation Trust and Manchester Cancer Research Centre,Manchester,Regno Unito

  • AbbVie Inc ,North Chicago, IL,Vereinigte Staaten

  • AbbVie Inc ,North Chicago, IL,Estados Unidos

  • University of Michigan, MI.

  • University of Michigan Comprehensive Cancer Center,Ann Arbor, MI,Vereinigte Staaten

  • Vejle Hospital,Vejle,Дания

  • Icahn School of Medicine at Mount Sinai, New York, New York, United States

  • 4th Department of Internal Medicine - Hematology,University Hospital Hradec Kralove,Hradec Kralove,Rep. Ceca

  • Fundacion Jimenez Diaz University Hospital, Health Research Institute IIS-FJD,Madrid,Spagna

  • Department of Hematology,AZ Sint-Jan Hospital,Bruges,Belgique

  • Universitair Ziekenhuis Gent, Ghent, Belgium

  • Vejle Hospital, Vejle, Denmark

  • Department of Hematology,AZ Sint-Jan Hospital,Bruges,Belgique

  • 4th Department of Internal Medicine - Hematology,University Hospital Hradec Kralove,Hradec Kralove,Rep. Ceca

  • AbbVie, N Chicago, USA

Locations

  • Denmark

  • Belgium

  • Czech Republic

  • United States

  • United Kingdom

  • Spain

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Diffuse large B-cell lymphoma

Biomarkers

  • Cytokeratin 20

  • Twist-related protein 1

Drug/Treatment

  • Cyclophosphamide

  • Cyclophosphamide Injection

  • Vincristine

  • Doxorubicin

  • Prednisone

  • Rituximab

Outcome

  • N/A

Study Design

  • N/A

Phase

  • I/II

Study Id's

  • NCT04663347

Sponsors

  • N/A

Result

  • N/A

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