// App-Quantinova.ai

P1161 : ASPEN: LONG-TERM FOLLOW-UP RESULTS OF A PHASE 3 RANDOMIZED TRIAL OF ZANUBRUTINIB (ZANU) VS IBRUTINIB (IBR) IN PATIENTS (PTS) WITH WALDENSTRÖM MACROGLOBULINEMIA (WM)

Researchers

Presenter

  • Meletios Dimopoulos

Principal Investigators

  • Shirley D'Sa

  • Wojciech Jurczak

  • Hui-Peng Lee

  • Gavin Cull

  • Roger G. Owen

  • Paula Marlton

  • Bjorn E. Wahlin

  • Ramon Garcia-Sanz

  • Helen McCarthy

  • Stephen Mulligan

  • Alessandra Tedeschi

  • Jorge J. Castillo

  • Jaroslaw Czyz

  • Carlos Fernandez De Larrea Rodriguez

  • David Belada

  • Edward Libby

  • Jeffrey Matous

  • Marina Motta

  • Tanya Siddiqi

  • Monica Tani

  • Marek Trneny

  • Monique Minnema

  • Christian Buske

  • Veronique Leblond

  • Steven P. Treon

  • Judith Trotman

  • Wai Y. Chan

  • Jingjing Schneider

  • Heather Allewelt

  • Aileen Cohen

  • Jane Huang

  • Constantine S. Tam

Medical Centers

  • FN Hradec Kralove,Hradec Králové,Rep. Ceca

  • Hospital Clínic Barcelona,Barcelona,Испания

  • Vseobecna fakultni nemocnice v Praze,Prague,Rep. Ceca

  • BeiGene USA, Inc.,San Mateo, CA,Verenigde Staten

  • Royal North Shore Hospital,Sydney

  • Ospedale Civile S.Maria delle Croc,AUSL Ravenna,Italy

  • Hospital Universitario de Salamanca,Salamanca,España

  • Nephrology, Royal North Shore Hospital, Sydney, New South Wales, Australia

  • Royal Melbourn

  • Dana-Farber Cancer Institute Boston,Boston,Stati Uniti

  • Ospedale Civile S.Maria delle Croc,AUSL Ravenna,Italy

  • National and Kapodistrian University of Athens, Athens, Greece

  • Karolinska Universi

  • FN Hradec Kralove,Hradec Králové,Tschechische Republik

  • Maria Skłodowska Curie National Research Institute of Oncology,Krakow,Polonia

  • Royal Bournemouth and Christchurch Hospital,Bournemouth,Reino Unido

  • City of Hope National Medical Center,Duarte,États-unis

  • Maria Skłodowska Curie National Research Institute of Oncology,Krakow,Polonia

  • Concord Repatriation General Hospital,S

  • Royal Bournemouth and Christchurch Hospital,Bournemouth,Reino Unido

  • Centre for Waldenström's Macroglobulinemia and Associated Disorders, University College London Hospital Foundation Trust,London,Royaume-uni

  • AO Spedali Civili di Brescia,Lombardia,Italia

  • Hematology,University Medical Center Utrecht,Utrecht,Países Bajos

  • Concord Repatriation General Hospital, New South Wales, Australia

  • Royal North Shore Hospital, Greenwich, New South Wales, Australia

  • Royal Melbourne Hospital, Parkville, Australia

  • Sorbonne University, Pitié Salpêtrière Hospital,Paris,Frankrijk

  • Hospital Universitario De Salamanca-IBSAL, Salamanca, Spain

  • Hospital Clinic Barcelona, Barcelona, Spain

  • Princess Alexandra Hospital, University of Queensland,Brisb

  • Hospital Clinic Barcelona,

  • Vseobecna fakultní nemocnice v Praze,Prague,Tchèque, République

  • CCC Ulm - Universitätsklinikum Ulm,Ulm, Baden-Württemberg,Deutschland

  • National and Kapodistria

  • Nephrology, Royal North Shore Hospital, Sydney, New South Wales, Australia

  • Concord Repatriation General Hospital, Sydney, Australia

  • National and Kapodistrian University of Athens, Athens, Greece

  • Vseobecna fakultni nemocnice v Praze,Prague,Rep. Ceca

  • Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń,Bydgoszcz,Polen

  • Karolinska Universitetssjukhuset and Karolinska Institutet,Stockholm,Svezia

  • Colorado Blood Cancer Institute,Denver,Estados Unidos

  • Concord Repatriation General Hospital, New South Wales, Australia

  • Centre for Waldenström's Macroglobulinemia and Associated Disorders, University College London Hospital Foundation Trust,London,Royaume-uni

  • Hospital Clinic Barcelona, Barcelona, Spain

  • Sorbonne University, Pitié Salpêtrière Hospital,Paris,Frankrijk

  • AO Spedali Civili di Brescia,Lombardia,Italia

  • Karolinska Universitetssjukhuset and Karolinska Institutet,Stockholm,Svezia

  • University Medical Center Utrecht, Utrecht, Netherlands

  • Dana-Farber Cancer Institute, Boston, MA, United States

  • Hospital Universitario De Salamanca-IBSAL, Salamanca, Spain

  • University of Washington/Seattle Cancer Care Alliance - Clinical Research,Seattle, WA,Stati Uniti

  • FN Hradec Kralove

  • Grande Ospedale Metropolitano Niguarda, Milan, Italy

  • City of Hope National Medical Center, Duarte, CA

  • Ospedale Civile S.Maria delle Croc,AUSL Ravenna,Italy

  • AO Spedali Civili di Brescia,Lombardia,Italia

  • Maria Sklodowska-Curie Institute of Oncology, Warsaw, Poland

  • Flinders University Medical Centre, Adelaide, Australia

  • Princess Alexandra Hospital and University of Queensland, Brisbane, Australia

  • Princess Alexandra Hospital and University of Queensland, Brisbane, Australia

  • Sir Charles Gairdner Hospital, University of Western Australia, Nedlands, Australia

  • Colorado Blood Cancer Institute,Denver,Estados Unidos

  • University Medical Center Utrecht, Utrecht, Netherlands

  • Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń,Bydgoszcz,Polen

  • Ospedale Civile S.Maria delle Croc,AUSL Ravenna,Italy

  • Monash Health and Monash University,Clayton, Victoria,Australien

  • Karolinska Universitetssjukhuset and Karolinska Institutet,Stockholm,Svezia

  • Sir Charles Gairdner Hospital, University of Western Australia, Nedlands, Australia

  • Monash Health a

  • Dana-Farber Cancer...

  • Hospital Universitario De Salamanca-IBSAL, Salamanca, Spain

  • Colorado Blood Cancer Institute,Denver,Estados Unidos

  • Colorado Blood Cancer Institute,Denver,Vereinigte Staaten

  • Vseobecna fakultni nemocnice v Praze,Prague,Rep. Ceca

  • Monash Health and Monash University,Clayton, Victoria,Australien

  • Hospital Universitario de Salamanca,Salamanca,España

  • Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń,Bydgoszcz,Polen

  • Sorbonne University, Pitié Salpêtrière Hospital,Paris,Frankrijk

  • University of Washington/Seattle Cancer Care Alliance - Clinical Research,Seattle, WA,Stati Uniti

  • BeiGene USA, Inc,San Mateo,United States

  • Maria Skłodowska Curie National Research Institute of Oncology,Krakow,Polonia

  • BeiGene USA, Inc.,San Mateo, CA,Stati Uniti

  • Hospital Universitario De Salamanca-IBSAL, Salamanca, Spain

  • Hematology,University Medical Center Utrecht,Utrecht,Países Bajos

  • Ospedale

  • CCC Ulm - Universitätsklinikum Ulm,Ulm, Baden-Württemberg,Deutschland

  • Colorado Blood Cancer Institute,Denver,Vereinigte Staaten

  • Dana-Faber Cancer Institute,Boston,Estados Unidos

  • Hospital Clinic Barcelona, Barcelona, Spain

  • Royal Bournemouth and Christchurch Hospital

  • AO Spedali Civili di Brescia,Lombardia,Italia

  • University Medical Center Utrecht,

  • Colorado Blood Cancer Institute,Denver,Estados Unidos

  • University Medical Center Utrecht, Utrecht, Netherlands

  • FN Hradec Kralove,Hradec Králové,Tchèque, République

  • St. James University Hospital,Leeds,Vereinigtes Königreich

  • Flinders University Medical Centre, Adelaide, Australia

  • BeiGene USA, Inc.,San Mateo,États-unis

  • Grande Ospedale Metropolitano Niguarda, Milan, Italy

  • Flinders Medical Centre

  • Royal Bournemouth Hospital,Bournemouth,Vereinigtes Königreich

  • St. James's University Hospital,Leeds,Reino Unido

  • Ospedale Civile S.Maria delle Croc,AUSL Ravenna,Italy

  • Grande Ospedale Metropolitano Niguarda, Milan, Italy

  • FN Hradec Kralove,Hradec Králové,Rep. Ceca

  • CCC Ulm-Universitätsklinikum Ulm, Baden-Württemberg, Germany

  • City of Hope National Medical Center, Duarte, CA

  • St. James University Hospital,Leeds,Vereinigtes Königreich

  • Princess Alexandra Hospital and University of Queensland, Brisbane, Australia

  • Sorbonne University, Piti

  • Royal Melbourne Hospital, Parkville, Australia

  • City of Hope National...

  • Monash Health and Monash University,Clayton, Victoria,Australien

  • Ospedale Civile S.Maria delle Croc,AUSL Ravenna,Italy

  • Vseobecna fakultní nemocnice v Praze,Prague,Tchèque, République

  • AO Spedali Civili di Brescia,Lombardia,Italia

  • City of Hope National Medical Center, Duarte, United States,

  • Royal Melbourne Hospital, Parkville, Australia

  • Flinders Medical Centre,Adelaide,Австралия

  • University Medical Center Utrecht, Utrecht, Netherlands

  • CCC Ulm-Universitätsklinikum Ulm, Baden-Württemberg, Germany

  • CCC Ulm-Universitätsklinikum Ulm, Baden-Württemberg, Germany

  • Collegium Medicum in Bydgoszcz, Nicolaus Co

  • 2Colorado Blood Cancer Institute Denver CO United States

  • CCC Ulm-Universitätsklinikum Ulm, Baden-Württemberg, Germany

  • Dana-Farber Cancer Institute, Boston, MA, United States

  • Nephrology, Royal North Shore Hospital, Sydney, New South Wales, Australia

  • Flinders University Medical Centre, Adelaide, Australia

  • BeiGene USA, Inc., San Mateo, CA

  • Sorbonne Université and Pitié Salpêtrière Hospital, Paris, France

  • Hospital Clinic Barcelona, Barcelona, Spain

  • Vseobecna fakultní nemocnice v Praze,Prague,Tchèque, République

  • Hospital Universitario de Salamanca,Salamanca,España

  • Hospital Clinic Barcelona, Barcelona, Spain

  • St James's University Hospital,Leeds,Royaume-uni

  • Sir Charles Gairdner Hospital, University of Western Australia, Nedlands, Australia

  • National and Kapodistrian University of Athens, Athens, Greece

  • Všeobecná fakultní nemocnice v Praze

  • Grande Ospedale Metropolitano Niguarda, Milan, Italy

  • Royal Bournemouth and Christchurch Hospital,Bournemouth,Reino Unido

  • Sir Charles Gairdner Hospital, University of Western Australia, Nedlands, Australia

  • Flinders University Medical Centre, Adelaide, Australia

  • University of Washington/Seattle Cancer Care Alliance - Clinical Research,Seattle, WA,Stati Uniti

  • AO Spedali Civili di Brescia,Lom

  • National and Kapodistrian University of Athens, Athens, Greece

  • FN Hradec Kralove,Hradec Králové,Rep. Ceca

  • St. James's University Hospital, Leeds, United Kingdom

  • St. James's University Hospital,Leeds,Reino Unido

  • BeiGene USA, Inc.,San Mateo, CA,Verenigde Staten

  • St. James University Hospital,Leeds,Соедин

  • Dana-Farber Cancer Institute, Boston, MA

  • Karolinska Universitetssjukhuset and Karolinska Institutet,Stockholm,Svezia

  • AO Spedali Civili di Brescia,Lombardia,Italia

  • BeiGene USA, Inc.,San Mateo, CA,Estados Unidos

  • Karolinska Universitetssjukhuset and Karolinska Institutet,Stockholm,Svezia

  • FN Hradec Kralove,Hradec Králové,Rep. Ceca

  • Royal Melbourne Hospital, Parkville, Australia

  • Hospital Universitario de Burgos

  • FN Hradec Kralove,Hradec Králové,Rep. Ceca

  • City of Hope National Medical Center, Duarte, United States,

  • Hospital Clinic Barcelona, Barcelona, Spain

  • Grande Ospedale Metropolitano Niguarda, Milan, Italy

  • City of Hope National Medical Center, Duarte, United States,

  • Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń,Bydgoszcz,Polen

  • Hematology,University Medical Center Utrecht,Utrecht,Países Bajos

  • Royal Melbourne Hospital, Parkville, Australia

  • Dana-Farber Cancer Institute, Boston, MA, United States

  • AO Spedali Civili di Brescia,Lombardia,Italia

  • Monash Health and Monash University,Clayton, Victoria,Australien

  • Flinders University Medical Centre, Adelaide, Australia

  • National and Kapodistrian University of Athens, Athens, Greece

  • Hospital Clínic de Barcelona,Barcelona,Espanha

  • Grande Ospedale Metropolitano Niguarda, Milan, Italy

  • Royal Bournemouth and Christchurch Hospital,Bournemouth,Royaume-uni

  • FN Hradec Kralove,Hradec Králové,Tschechische Republik

  • University of Washington/Seattle Cancer Care Alliance - Clinical Research,Seattle, WA,Stati Uniti

  • Centre for Waldenström's Macroglobulinemia and Associated Disorders, University College London Hospital Foundation Trust,London,Royaume-uni

Locations

  • United States

  • Greece

  • Australia

  • United Kingdom

  • Poland

  • Sweden

  • Mexico

  • Spain

  • Sierra Leone

  • Canada

  • Italy

  • Venezuela

  • Czech Republic

  • Netherlands

  • Germany

  • France

Companies

  • N/A

Study Components

Therapeutic Area

  • Gastroenterology (GU)

Disease

  • N/A

Biomarkers

  • C-X-C motif chemokine receptor 4

Drug/Treatment

  • Ibrutinib

Outcome

  • N/A

Study Design

  • Randomized

  • Cohort

Phase

  • III

Study Id's

  • NCT03053440

Sponsors

  • N/A

Result

  • N/A

Copyright © 2026. QuantiNova All rights reserved