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P1050 : THROMBOCYTOPENIC MYELOFIBROSIS (MF) PATIENTS PREVIOUSLY TREATED WITH A JAK INHIBITOR IN A PHASE 3 RANDOMIZED STUDY OF MOMELOTINIB (MMB) VERSUS DANAZOL (DAN) [MOMENTUM]

Researchers

Presenter

  • Alessandro Vannucchi

Principal Investigators

  • Aaron Gerds

  • Haifa Kathrin Al-Ali

  • David Lavie

  • Andrew Kuykendall

  • Sebastian Grosicki

  • Alessandra Iurlo

  • Yeow Tee Goh

  • Mihaela Lazaroiu

  • Miklos Egyed

  • Maria Laura Fox

  • Donal McLornan

  • Andrew Perkins

  • Sung-Soo Yoon

  • Vikas Gupta

  • Jean-Jacques Kiladjian

  • Rafe Donahue

  • Jun Kawashima

  • Srdan Verstovsek

Medical Centers

  • University Hospital of Halle,Halle,Deutschland

  • S.C. Policlinica de Diagnostic Rapid S.A.,Brasov,Romania

  • Seoul National University Hospital, Seoul, Korea

  • University Hospital of Halle,Halle,Deutschland

  • Sierra Oncology, Inc. ,San Mateo, CA,U

  • Moffitt Cancer Center,Tampa,Verenigde Staten

  • University Hospital of Halle,Halle,Hongarije

  • Aphp Saint-Louis Hospital, Paris, France

  • The University of Texas MD Anderson Cancer Canter, Houston, TX

  • Moffitt Cancer Center, Tampa, FL

  • Mofitt Cancer Center,Tampa, FL,Estados Unidos

  • Deakin University, Melbourne, Australia

  • Saint Louis Hospital, APHP, Paris, France

  • Deakin University, Melbourne, Australia

  • Sierra Oncology, Inc. ,San Mateo, CA,U

  • Cleveland Clinic Department of Hematology and Medical Oncology,Avon,United States

  • Sierra Oncology, Inc. ,San Mateo, CA,U

  • Somogy County Mór Kaposi General Hospital, Kaposvár, Hungary

  • Sierra Oncology, Inc. ,San Mateo, CA,U

  • Sierra Oncology, Inc. ,San Mateo, CA,U

  • Sierra Oncology, Inc. ,San Mateo, CA,U

  • Guy's and St Thomas' NHS Foundation Trust,London,Royaume-uni

  • Department of Hematology, Vall d'Hebron Institute of Oncology (VHIO),

  • Center for Research and Center for Research and Innovation of Myeloproliferative Neoplasms, AOU Careggi, University of Florence, Florence, Italy

  • Saint-Louis Hospital (AP-HP),Paris,Frankrijk

  • University Hospital of Halle,Halle,Венгрия

  • Hadassah-Hebrew-University-Medical-Cente, Jerusalem, Israel

  • Center for Research and Center for Research and Innovation of Myeloproliferative Neoplasms, AOU Careggi, University of Florence, Florence, Italy

  • Medical University of Silesia in Katowice,Katowice,Polonia

  • S.C. Policlinica de Diagnostic Rapid S.A.,Brasov,Romania

  • Department of Hematology, Vall d'Hebron Institute of Oncology (VHIO), Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus,Barcelona,Spanien

  • Monash University,Melbourne,Австралия

  • Singapore General Hospital, Singapore, Singapore

  • Sierra Oncology, Inc. ,San Mateo, CA,U

  • University Hospital of Halle,Halle,Deutschland

  • Foundation IRCCS Ca' Granda Ospedale Maggiore

  • Moffitt Cancer Center, Tampa, Florida, United States

  • Princess Margaret Cancer Center, Toronto, ON, Canada

  • Saint-Louis Hospital (AP-HP),Paris,Frankrijk

  • Sierra Oncology, Inc. ,San Mateo, CA,U

  • Cleveland Clinic Department of Hematology and Medical Oncology,Avon,United States

  • University of Texas MD Anderson Cancer Center, Houston, Texas, United States

  • Somogy County Mór Kaposi General Hospital, Kaposvár, Hungary

  • Singapore General Hospital, Singapore, Singapore

  • Sierra Oncology, Inc. ,San Mateo, CA,U

  • The University of Texas MD Anderson Cancer Canter, Houston, TX

  • UT Health San Antonio Cancer Center, San Antonio, TX

  • IRCCS Ca Granda, Ospedale Maggiore Policlinico, Milano, Italy

  • Seoul National University Bundang Hospital,Seongnam,Corée, République De

  • Princess Margaret Cancer Center, Toronto, ON, Canada

  • Medical University of Vienna,

  • Deakin University, Melbourne, Australia

  • Somogy County Mór Kaposi General Hospital, Kaposvár, Hungary

  • Guy's And St Thomas NHS Foundation Trust, London, United Kingdom

  • Singapore General Hospital, Singapore, Singapore

  • Internal Medicine,Seoul National University Hospital ,Seoul,South Korea，Republic

  • Guy's and St Thomas' NHS Foundation Trust,London,Royaume-uni

  • Hadassah Hebrew University Medical Center,Jer

  • Princess Margaret Cancer Center, Toronto, ON, Canada

  • S.C. Policlinica de Diagnostic Rapid S.A.,Brasov,Romania

  • UT Health San Antonio Cancer Center, San Antonio, TX

  • University Hospital of Halle,Halle,Deutschland

  • UT Health San Antonio Cancer Center,San Antonio, TX,Vereinigte Staaten

  • Cleveland Clinic Department of Hematology and Medical Oncology,Avon,United States

  • UT Health San Antonio Cancer Center,San Antonio, TX,Vereinigte Staaten

  • Somogy County Mór Kaposi General Hospital, Kaposvár, Hungary

  • Policlinica de Diagnostic Rapid Brasov,Brasov,Roemenië

  • Singapore General Hospital, Singapore, Singapore

  • Somogy County Mór Kaposi General Hospital, Kaposvár, Hungary

  • Singapore General Hospital, Singapore, Singapore

  • Moffitt Cancer Center,Tampa, FL,Stati Uniti

  • Medical University of Silesia in Katowice,Katowice,Polonia

  • Moffitt Cancer Center,Tampa, FL,Stati Uniti

  • Sierra Oncology, Inc. ,San Mateo, CA,U

  • Somogy County Mór Kaposi General Hospital, Kaposvár, Hungary

  • Guy's and St Thomas' NHS Foundation Trust,London,Reino Unido

  • Policlinica de Diagnos

  • Medical University of Silesia,Katowice,Польша

  • Medical University of Silesia, Zabrze, Poland

  • The University of Tokyo

  • Medical University of Silesia , Katowice,Polen

  • Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico,Milano,Italie

  • Cleveland Clinic Department of Hematology and Medical Oncology,Avon,United States

  • University Hospital of Halle,Halle,Deutschland

  • Department of Hematology, Vall d'Hebron Institute of Oncology (VHIO), Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus,Barcelona,Spanien

  • Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico,Milano,Italie

  • Center for Research and Center for Research and Innovation of Myeloproliferative Neoplasms, AOU Careggi, University of Florence, Florence, Italy

  • Center Research and Innovation of Myeloproliferativ

  • Seoul National University Hospital,Seoul,Корея, южная

  • Seoul National University Hospital, Seoul, Korea

  • S.C. Policlinica de Diagnostic Rapid S.A.,Brasov,Romania

  • Saint-Louis Hospital (AP-HP),Paris,Frankrijk

  • Seoul National University Hospital, Seoul, Korea

  • Hadassah-Hebrew-University-Medical-Cente, Jerusalem, Israel

  • Saint Louis Hospital,Paris,Франция

  • UT Health San Antonio Cancer Center,San Antonio, TX,Estados Unidos

  • Cleveland Clinic Department of Hematology and Medica

  • UT Health San Antonio Cancer Center, San Antonio, TX

  • Princess Margaret Cancer Center, Toronto, ON, Canada

  • Guy's and St. Thomas' NHS Foundation Trust,London,Vereinigtes Königreich

  • Singapore General Hospital, Singapore, Singapore

  • Moffitt Cancer Center,Tampa,Verenigde Staten

  • Deakin University, Melbourne, Australia

  • Guy's and St Thomas' NHS Foundation Trust,London,Royaume-uni

  • Sierra Oncology, Inc. ,San Mateo, CA,U

  • Saint-Louis Hospital (AP-HP),Paris,Frankrijk

  • Sierra Oncology, Inc. ,San Mateo, CA,U

  • Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico,Milano,Italie

  • Singapore General Hospital, Singapore, Singapore

  • Policlinica de Diagnostic Rapid Brasov,Brasov,Roemenië

  • The University of Texas MD Anderson Cancer Canter, Houston, TX

  • Deakin University, Melbourne, Australia

  • University Hospital of Halle,Halle,Deutschland

  • Hadassah-Hebrew-University-Medical-Cente, Jerusalem, Israel

  • The University of Texas, MD Anderson Cancer Center,Houston, TX,Verenigde Staten

  • Somogy County Mór Kaposi General Hospital,Ka

  • Policlinica de Diagnostic Rapid Brasov,Brasov,Roemenië

  • University Hospital of Halle,Halle,Deutschland

Locations

  • United States

  • Germany

  • Hungary

  • Israel

  • Poland

  • Italy

  • Singapore

  • Romania

  • Venezuela

  • United Kingdom

  • Australia

  • Republic of South Korea

  • Canada

  • France

  • Senegal

  • Turkey

  • Republic of South Korea

Companies

  • N/A

Study Components

Therapeutic Area

  • Blood/haematological Diseases

  • Oncology (ONC)

  • Central Nervous System (CNS)

Disease

  • Thrombocytopenia

  • Myelofibrosis

  • Hematoma

  • Anemia

Biomarkers

  • N-Acylethanolamine acid amidase

  • Janus kinase

  • Red Blood Cells

Drug/Treatment

  • Momelotinib

  • Danazol

Outcome

  • N/A

Study Design

  • Randomized

  • Placebo Control

Phase

  • III

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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