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P1162 : ZANUBRUTINIB IN OLDER PATIENTS (PTS) WITH RELAPSED/REFRACTORY (R/R) MARGINAL ZONE LYMPHOMA (MZL): SUBGROUP ANALYSIS OF THE MAGNOLIA STUDY

Researchers

Presenter

  • Stephen Opat

Principal Investigators

  • Alessandra Tedeschi

  • Pamela McKay

  • Henry Chan

  • Jie Jin

  • Mingyuan Sun

  • Magdalena Sobieraj-Teague

  • Pier Luigi Zinzani

  • Morton Coleman

  • Peter Browett

  • Xiaoyan Ke

  • Craig A. Portell

  • Catherine Thieblemont

  • Kirit Ardeshna

  • Fontanet Bijou

  • Patricia Walker

  • Shir-Jing Ho

  • Ke-Shu Zhou

  • Melannie Co

  • Jianfeng Xu

  • Joanna Anderson

  • Chris Tankersley

  • Jane Huang

  • Judith Trotman

Medical Centers

  • Colorectal Unit, Flinders Medical Centre, Bedford Park, South Australia, Australia

  • Beatson West of Scotland Cancer Centre, Glasgow, United Kingdom

  • Henan Cancer Hospital, Zhengzhou, China

  • University of Virginia Health System, Charlottesville, United States

  • Institute of Hematology 'Seràgnoli'

  • Concord Repatriation General Hospital, University of Sydney,Concord, New South Wales,Australie

  • BeiGene (Beijing) Co., L

  • Peninsula Private Hospital, Frankston Victoria, Australia

  • Auckland City Hospital,Grafton,Nieuw Zeeland

  • Institut Bergonie, Bordeaux, France

  • The First Affiliated Hospital of Zhejiang University, Hangzhou, China, Beijing, China

  • University College London Hospitals NHS Trust, London, United Kingdom

  • The First Affiliated Hospital of Zhejiang University, Hangzhou, China, Beijing, China

  • Institut Bergonié,Bordeaux,Frankreich

  • Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College,Tianjin,Chine

  • Peking University Third Hospital Beijing China

  • Henan Cancer Hospital, Zhengzhou, China

  • Beatson West of Scotland Cancer Centre, Glasgow, United Kingdom

  • Levine Cancer Institute/Atrium Health,Charlotte,Verenigde Staten

  • Beatson West of Scotland Cancer Centre,Glasgow,Vereinigtes Königreich

  • Institut Bergonie, Bordeaux, France

  • North Shore Hospital,Auckland,Nueva Zelanda

  • North Shore Hospital,Auckland,Nueva Zelanda

  • University College London Hospitals,London,Royaume-uni

  • Institut Bergonié,Bordeaux,Франция

  • Auckland City Hospital,Grafton,Nieuw Zeeland

  • BeiGene (Beijing) Co., Ltd., Beijing, China and BeiGene USA, Inc.,San Mateo, CA,Vereinigte Staaten

  • University of Virginia Health System, VA

  • Auckland City Hospital,Grafton,Новая Зеландия

  • APHP, Hôpital Saint-Louis, Hemato-oncology, Paris University Diderot, Paris, France

  • University College London Hospitals,London,Vereinigtes Königreich

  • Institute of Hematology, University of Bologna, Bologna, Italy

  • Peninsula Private Hospital, Frankston Victoria, Australia

  • Henan Cancer Hospital, Zhengzhou, China

  • The First Affiliated Hospital of Zhejiang University, Hangzhou, China, Beijing, China

  • Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College,Tianjin,Chine

  • Box Hill Hospital,Box Hill, Victoria,Austrália

  • Henan Cancer Hospital, Zhengzhou, China

  • Box Hill Hospital, Box Hill, Australia

  • Box Hill Hospital,Box Hill, Victoria,Austrália

  • Levine Cancer Institute/Atrium Health,Charlotte,Verenigde Staten

  • APHP, Hôpital Saint-Louis, Hemato-oncology, Paris University Diderot, Paris, France

  • Concord Repatriation General Hospital, University of Sydney,Concord, New South Wales,Australie

  • Grande Ospedale Metropolitano Niguarda, Milan, Italy

  • Concord Repatriation General Hospital, University of Sydney,Concord, New South Wales,Australie

  • Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medi

  • Institut Bergonie, Bordeaux, France

  • Flinders Medica

  • The Christie Hospital NHS Foundation Trust,Manchester,Royaume-uni

  • North Shore Hospital,Auckland,Nueva Zelanda

  • Haematology,The Christie NHS Foundation Trust,Manchester,Vereinigtes Königreich

  • Levine Cancer Institute/Atrium Health,Charlotte,Verenigde Staten

  • Colorectal Unit, Flinders Medical Centre, Bedford Park, South Australia, Australia

  • Beatson West of Scotland Cancer Centre, Glasgow, United Kingdom

  • Institute of Hematology, University of Bologna, Bologna, Italy

  • BeiGene (Beijing) Co., Ltd., Beijing, China and BeiGene USA, Inc.,San Mateo, CA,Vereinigte Staaten

  • Peninsula Private Hospital, Frankston Victoria, Australia

  • Institut Bergonié,Bordeaux,Frankreich

  • Clinical Research Alliance/Weill Cornell Medicine,New York City, NY,United States

  • Monash Health a

  • University of Virginia Health System,Charlottesville, VA,États-unis

  • BeiGene (Beijing) Co., Ltd., Beijing, China and BeiGene USA, Inc.,San Mateo, CA,Vereinigte Staaten

  • University of Virginia Health System,Charlottesville, VA,États-unis

  • Levine Cancer Institute/Atrium Health,Charlotte,Verenigde Staten

  • Monash Health and Monash University,Clayton, Victoria,Australien

  • Clinical Research Alliance/Weill Cornell Medicine,New York City, NY,United States

  • The Christie Hospital NHS Foundation Trust,Manchester,Royaume-uni

  • University of Virginia Health System, Charlottesville, United States

  • Institute of Hematology, University of Bologna, Bologna, Italy

  • BeiGene (Beijing) Co., Ltd., Beijing, China and BeiGene USA, Inc.,San Mateo, CA,Vereinigte Staaten

  • Clinical Research Alliance/Weill Cornell Medicine,New York City, NY,United States

  • Colorectal Unit, Flinders Medical Centre, Bedford Park, South Australia, Australia

  • Grande Ospedale Metropolitano Niguarda, Milan, Italy

  • University College London, London, UK

  • Peninsula Private Hospital, Frankston Victoria, Australia

  • Levine Cancer Institute/Atrium Health,Charlotte,Verenigde Staten

  • North Shore Hospital,Auckland,Nueva Zelanda

  • Grande Ospedale Metropolitano Niguarda, Milan, Italy

  • Box Hill Hospital,Box H

  • Clinical Research Alliance/Weill Cornell Medicine,New York City, NY,United States

  • Peking University Third H

  • Monash Health and Monash University,Clayton, Victoria,Australien

  • University College London, London, UK

  • University College London, London, UK

  • The Christie Hospital NHS Foundation Trust,Manchester,Royaume-uni

  • North Shore Hospital,Auckland,新西兰

  • Auckland City Hospital,Grafton,Nieuw Zeeland

  • North Shore Hosp, Auckland, New Zealand

  • The Christie NHS Foundation Trust, Manchester,

  • Beatson West of Scotland Cancer Centre,Glasgow,Royaume-uni

  • Auckland City Hospital,Grafton,新西兰

  • Box Hill Hospital,Box Hill, Victoria,Austrália

  • Auckland City Hospital,Grafton,Nieuw Zeeland

  • University of Virginia Health System,Charlottesville, VA,États-unis

  • Box Hill Hospital,Box Hill, Victoria,Австралия

  • Box Hill Hospital,Box Hill, Victoria,Austrália

  • Beatson West of Scotland Cancer Centre,Glasgow,Vereinigtes Königreich

  • St. George Hos

  • North Shore Hospital,Auckland,Nueva Zelanda

  • St. George Hospital,Kogarah, New South Wells,Austrália

  • The Christie Hospital NHS Foundation Trust,Manchester,Royaume-uni

  • University College London Hospitals,London,Vereinigtes Königreich

  • Grande Ospedale Metropolitano Niguarda, Milan, Italy

  • The First Affiliated...

  • Institute of Hematology, University of Bologna, Bologna, Italy

  • APHP, Hôpital Saint-Louis, Hemato-oncology, Paris University Diderot, Paris, France

  • North Shore Hospital,Auckland,Nueva Zelanda

  • Auckland City Hospital,Grafton,Nieuw Zeeland

  • St. George Hospital,Kogarah, New South Wells,Austrália

  • APHP, Hôpital Saint-Louis, Hemato-oncology, Paris University Diderot, Paris, France

  • Beatson West of Scotland

  • Institute of Hematology an

  • Peking University Third Hospital Beijing China

  • Colorectal Unit, Flinders Medical Centre, Bedford Park, South Australia, Australia

  • Clinical Research Alliance/Weill Cornell Medicine,New York City, NY,United States

  • St. George Hospital,Kogarah, New South Wells,Austrália

  • St George Private Hospital, Kogarah, New South Wales, Australia

  • Institut Bergonie, Bordeaux, France

  • Auckland City Hospital,Grafton,Nieuw Zeeland

  • Peking University Third Hospital Beijing China

  • Peninsula Private Hospital, Frankston Victoria, Australia

  • Levine Cancer Institute, Atrium Health, Charlotte, NC

  • North Shore Hospital,Auckland,Новая Зеландия

  • Grande Ospedale Metropolitano Niguarda, Milan, Italy

  • Monash Health and Monash University,Clayton, Victoria,Australien

  • Auckland City Hospital,Grafton,Nieuw Zeeland

  • St. George Hospital,Kogarah, New South Wells,Austrália

  • Grande Ospedale Metropolitano Niguarda, Milan, Italy

  • Concord Repatriatio

  • Monash Health and Monash University,Clayton, Victoria,Australien

Locations

  • United States

  • Australia

  • Italy

  • United Kingdom

  • New Zealand

  • China

  • France

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Gastroenterology (GU)

Disease

  • Mucosa-associated lymphoid tissue lymphoma

Biomarkers

  • N/A

Drug/Treatment

  • BGB-3111

  • L-Tyrosine

Outcome

  • N/A

Study Design

  • Single Arm

  • Multicenteric

Phase

  • II

Study Id's

  • NCT03846427

Sponsors

  • N/A

Result

  • N/A

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