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S166 : MAGROLIMAB IN COMBINATION WITH AZACITIDINE FOR PATIENTS WITH UNTREATED HIGHER-RISK MYELODYSPLASTIC SYNDROMES (HR MDS): 5F9005 PHASE 1B STUDY RESULTS

Researchers

Presenter

  • David A Sallman

Principal Investigators

  • Adam S Asch

  • Eunice S Wang

  • Joseph G Jurcic

  • Terrence J Bradley

  • Ian W Flinn

  • Daniel A Pollyea

  • Tiffany N Tanaka

  • Joshua F Zeidner

  • Guillermo Garcia-Manero

  • Deepa Jeyakumar

  • Lin Gu

  • Mark Chao

  • Carol O'Hear

  • Indu Lal

  • Paresh Vyas

  • Naval Daver

Medical Centers

  • City of Hope National Medical Center, Duarte, United States,

  • Lineberger Comprehensive Cancer Center,University of North Carolina,Chapel Hill,Vereinigte Staaten

  • University of Colorado School of Medicine, Denver, TX.

  • Lineberger Comprehensive

  • Roswell Park Comprehensive Cancer Center, Buffalo, NY

  • Lineberger Comprehensive Cancer Center at the University of North Carolina, Chapel Hill, NC

  • Tennessee Oncology,Nashville,Vereinigte Staaten

  • Moffitt Cancer Center,Tampa, FL,Stati Uniti

  • University of California San Diego Moores Cancer Center,San Diego,United States

  • Gilead Sciences, Inc.,Foster City,Vereinigte Staaten

  • City of Hope National Medical Center,Duarte,États-unis

  • University of California Irvine,Orange,États-unis

  • University of California Merced,

  • Weatherall Institute of Molecular Medicine, MRC

  • City of Hope National Medical Center, Duarte, United States,

  • Columbia University Medical Center,New York,États-unis

  • Gilead Sciences, Inc., Foster City, CA, United States.

  • Moffitt Cancer Center, Tampa, Florida, United States

  • MRC Weatherall Institute of Molecular Medicine, University of Oxford,Oxford,Vereinigtes Königreich

  • Gilead Sciences, Inc.,Foster City,Stati Uniti

  • Mofitt Cancer Center,Tampa, FL,Estados Unidos

  • University of Texas MD Anderson Cancer Center, Houston, Texas, United States

  • City of Hope National Medical Center, Duarte, CA

  • Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL

  • The University of Texas MD Anderson Cancer Canter, Houston, TX

  • University of California San Diego Moores Cancer Center,San Diego,United States

  • Lineberger Comprehensive Cancer Center at the University of North Carolina, Chapel Hill, NC

  • University of California San Diego Moores Cancer Center,San Diego,United States

  • The University of Texas MD Anderson Cancer Canter, Houston, TX

  • The University of Texas MD Anderson Cancer...

  • Roswell Park Comprehensive Cancer Center,Buffalo,Estados Unidos

  • University of Colorado School of Medicine, Aurora, CO, United States

  • MRC Weatherall Institute of Molecular Medicine, University of Oxford,Oxford,Royaume-uni

  • University of California Irvine,Orange,Verenigde Staten

  • Lineberger Comprehensive Cancer Center at the University of North Carolina, Chapel Hill, NC

  • University of California Irvin,Irvine,Estados Unidos

  • Roswell Park Compr

  • Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL

  • Tennessee Oncology,Nashville,Stati Uniti

  • Sarah Cannon Research Institute, Nashville,United States

  • University of Colorado School of Medicine,Denver,Vereinigte Staaten

  • Columbia University Medical Center,New York,États-unis

  • Columbia University Medical Center,New York,Verenigde Staten

  • Tennessee Oncology,Nashville,Vereinigte Staaten

  • Roswell Park Comprehensive Cancer Center, Buffalo, NY

  • Medicine,Roswell Park Comprehensive Cancer Center,Buffalo,United States

  • Gilead Sciences, Inc.,Foster City,Stati Uniti

  • The University of Texas MD Anderson Cancer Canter, Houston, TX

  • Tennessee Oncology, Nashville, TN

  • Tennessee Oncology,Nashville,Vereinigte Staaten

  • Moffitt Cancer Center,Tampa,Verenigde Staten

  • Gilead Scie

  • Gilead Sciences, Inc.,Foster City,Vereinigte Staaten

  • Sarah Cannon Research Institute,Kansas City,Verenigde Staten

  • University of California San Diego Moores Cancer Center,San Diego,United States

  • University of California San Diego Moores Cancer Center,San Diego,United States

  • Columbia University Medical Center,New York,Verenigde Staten

  • University of California Irvine,Orange,Verenigde Staten

  • City of Hope National Medical Center, Duarte, CA

  • Columbia University Medical Center, New York, NY

  • Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL

  • Columbia University, New York, New York, United States

  • MRC Weatherall Institute of Molecular Medicine, University of Oxford,Oxford,Royaume-uni

  • Tennessee Oncology,Nashville,États-unis

  • Tennessee Oncology,Nashville,Estados Unidos

  • University of California, Davis, Davis, California, United States

  • University of Bologna

  • IGF Group, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom

  • City of Hope National Medical Center,Duarte,États-unis

  • Moffitt Cancer Center, Tampa, FL

  • Medicine,Roswell Park Comprehensive Cancer Center,Buffalo,United States

  • Roswell Park Comprehensive Cancer Center,Buffalo,Verenigde Staten

  • University of Colorado School of Medicine,Denver,Estados Unidos

  • Sarah Cannon Research Institute,Kansas City,Verenigde Staten

  • City of Hope National Medical Center, Duarte, United States,

  • University of Colorado School of Medicine,Denver,Vereinigte Staaten

  • Gilead Sciences, Inc.,Foster City,Stati Uniti

  • Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL

  • Moffitt Cancer Center,Tampa,Verenigde Staten

  • University of California Irvine,Orange,États-unis

  • Columbia University Medical Center, New York, NY

  • University of Colorado School of Medicine, Denver, TX.

  • Department of Leukemia,University of Texas MD Anderson Cancer Center,Houston,Vereinigte Staaten

  • Moffitt Cancer Center,Tampa, FL,Stati Uniti

Locations

  • United States

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Myelodysplastic Syndrome

Biomarkers

  • Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Epsilon

Drug/Treatment

  • Vidaza

Outcome

  • N/A

Study Design

  • Multinational

Phase

  • I

Study Id's

  • NCT03248479

  • NCT04313881

Sponsors

  • N/A

Result

  • N/A

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