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P989 : DYNAMIC CHANGES IN THE HISTONE H3 LYSINE 27 TRIMETHYLATION EPIGENETIC LANDSCAPE FOLLOWING RUXOLITINIB ADMINISTRATION

Researchers

Presenter

  • Graeme Greenfield

Principal Investigators

  • Mary Frances McMullin

  • Ken Mills

Medical Centers

  • Queen's University Belfast, Belfast, United Kingdom

  • PGJCCR,Queen's Universtiy Belfast,Belfast,Regno Unito

  • PGJCCR,Queen's Universtiy Belfast,Belfast,Regno Unito

  • PGJCCR,Queen's Universtiy Belfast,Belfast,Vereinigtes Königreich

  • PGJCCR,Queen's Universtiy Belfast,Belfast,Vereinigtes Königreich

  • PGJCCR,Queen's Universtiy Belfast,Belfast,Vereinigtes Königreich

  • PGJCCR,Queen's Universtiy Belfast,Belfast,Regno Unito

  • PGJCCR,Queen's Universtiy Belfast,Belfast,Regno Unito

  • PGJCCR,Queen's Universtiy Belfast,Belfast,Regno Unito

  • PGJCCR,Queen's Universtiy Belfast,Belfast,Regno Unito

  • Queen's University Belfast, Belfast, United Kingdom

  • PGJCCR,Queen's Universtiy Belfast,Belfast,Vereinigtes Königreich

  • PGJCCR,Queen's Universtiy Belfast,Belfast,Regno Unito

  • PGJCCR,Queen's Universtiy Belfast,Belfast,Vereinigtes Königreich

  • Queen's University Belfast, Belfast, United Kingdom

  • CME,Queen's Universit

  • PGJCCR,Queen's Universtiy Belfast,Belfast,Regno Unito

  • PGJCCR,Queen's Universtiy Belfast,Belfast,Vereinigtes Königreich

  • PGJCCR,Queen's Universtiy Belfast,Belfast,Regno Unito

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • N/A

Disease

  • N/A

Biomarkers

  • Enhancer of zeste homolog 2

  • Immunoglobulin G

  • Trimethylation of lysine 27 on histone H3

Drug/Treatment

  • Ruxolitinib phosphate

  • DMSO

  • EZH2

Outcome

  • N/A

Study Design

  • N/A

Phase

  • N/A

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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