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PB2176 : AN AUSTRALIAN/NEW ZEALAND RANDOMIZED TRIAL OF POST-TRANSPLANT CYCLOPHOSPHAMIDE IN MATCHED RELATED PERIPHERAL BLOOD STEM CELL TRANSPLANTS FOR ACUTE LEUKAEMIA OR MYELODYSPLASIA – ALLG BM12

Researchers

Presenter

  • David Curtis

Principal Investigators

  • Sushrut Patil

  • Duncan Purtill

  • David Ritchie

  • David Yeung

  • Clinton Lewis

  • Eric Wong

  • John Moore

  • Travis Perera

  • Madeleine King

  • Richard De Abreu Lourenco

  • Geoffrey Hill

  • John Reynolds

  • Siok Tey

  • David Gottlieb

Medical Centers

  • Haematology,Wellington Blood and Cancer Centre,Wellington,Neuseeland

  • Haematology Department, Royal Perth Hospital, Perth, Australia

  • Haematology and Bone Marrow Transplantation,Royal Brisbane and Women's Hospital,Brisbane,Australie

  • Pharmacology, St Vincent's Health Network, Sydney, Australia

  • Biostatistics Platform,Monash University,Melbourne,Australia

  • Centre for Health Technologies, University of Technology Sydney, Sydney, Australia.

  • Peter MacCallum Cancer Centre and Royal Melbourne Hospital, Melbourne, Australia

  • Clinical Haematology,Alfred Health,Melbourne,Australien

  • Clinical Haematology,Alfred Health,Melbourne,Австралия

  • Infectious Diseases, Alfred Hospital, Melbourne, Australia

  • Biostatistics Platform,Monash University,Melbourne,Australia

  • Clinical Haematology,Alfred Health,Melbourne,Australien

  • Pharmacology, St Vincent's Health Network, Sydney, Australia

  • Haematology and Bone Marrow Transplantation,Royal Brisbane and Women's Hospital,Brisbane,Australie

  • Biostatistics Platform,Monash University,Melbourne,Australia

  • School of Psychology, The University of Sydney, Sydney, Australia

  • Infectious Diseases, Alfred Hospital, Melbourne, Australia

  • Haematology and Bone Marrow Transplantation,Royal Brisbane and Women's Hospital,Brisbane,Australie

  • Haematology,Wellington Blood and Cancer Centre,Wellington,Neuseeland

  • Haematology,Westmead Hospital,Sydney,Австралия

  • Centre for Health Technologies, University of Technology Sydney, Sydney, Australia.

  • Medicine,Fred Hutch ,Seattle,USA

  • Haematology,Wellington Blood and Cancer Centre,Wellington,Neuseeland

  • Haematology,St Vincents Health Network,Sydney,Австралия

  • Haematology and Bone Marrow Transplantation,Royal Brisbane and Women's Hospital,Brisbane,Australie

  • Royal Adelaide Hospital,Adelaide,Австралия

  • Rheumatology Unit, Royal Adelaide Hospital, Adelaide, Australia

  • Medicine,Fred Hutch ,Seattle,United States

  • Haematology,Auckland City Hospital,Auckland,Nova Zelândia

  • Centre for Health Economics,University of Technology Sydney,Sydney,Австралия

  • Rheumatology, Austin Health, Melbourne, Australia

  • Medicine,Fred Hutch ,Seattle,United States

  • Rheumatology Unit, Royal Adelaide Hospital, Adelaide, Australia

  • Haematology,Wellington Blood and Cancer Centre,Wellington,Neuseeland

  • Haematology at Peter MacCallum Cancer Centre and The Royal Melbourne Hospital,Melbourne, VIC,Australie

  • Haematology and Bone Marrow Transplantation,Royal Brisbane and Women's Hospital,Brisbane,Australie

  • Haematology,Auckland City Hospital,Auckland,Nova Zelândia

  • Haematology and Bone Marrow Transplantation,Royal Brisbane and Women's Hospital,Brisbane,Австралия

  • School of Psychology, The University of Sydney, Sydney, Australia

  • Haematology, Westmead Hospital, Sydney, Australia

  • School of Psychology,University of Sydney,Sydney,Австралия

  • School of Psychology, The University of Sydney, Sydney, Australia

  • Centre for Health Technologies, University of Technology Sydney, Sydney, Australia.

  • Rheumatology, Austin Health, Melbourne, Australia

  • School of Psychology, The University of Sydney, Sydney, Australia

  • Rheumatology, Austin Health, Melbourne, Australia

  • Haematology,Auckland City Hospital,Auckland,Nova Zelândia

  • Fred Hutch,Seattle,Estados Unidos

  • Pharmacology, St Vincent's Health Network, Sydney, Australia

  • Haematology,Auckland City Hospital,Auckland,Nova Zelândia

  • Infectious Diseases, Alfred Hospital, Melbourne, Australia

  • Biostatistics Platform,Monash University,Melbourne,Australia

  • Medicine,Fred Hutch ,Seattle,Stati Uniti

  • Rheumatology Unit, Royal Adelaide Hospital, Adelaide, Australia

  • Rheumatology Unit, Royal Adelaide Hospital, Adelaide, Australia

  • Rheumatology, Austin Health, Melbourne, Australia

  • Rheumatology Unit, Royal Adelaide Hospital, Adelaide, Australia

  • Biostatistics Platform,Monash University,Melbourne,Australia

  • Infectious Diseases, Alfred Hospital, Melbourne, Australia

  • Medicine,Fred Hutch ,Seattle,United States

  • Haematology,Finoa Stanley Hospital,Perth,Australië

  • Pharmacology, St Vincent's Health Network, Sydney, Australia

  • Haematology Service,Fiona Stanley Hospital,Perth,Австралия

  • Haematology,Wellington Blood and Cancer Centre,Wellington,Neuseeland

  • Haematology at Peter MacCallum Cancer Centre and The Royal Melbourne Hospital,Melbourne, VIC,Australie

  • School of Psychology, The University of Sydney, Sydney, Australia

  • Haematology at Peter MacCallum Cancer Centre and The Royal Melbourne Hospital,Melbourne, VIC,Australie

  • Haematology, Westmead Hospital, Sydney, Australia

  • Haematology,Wellington Blood and Cancer Centre,Wellington,Neuseeland

  • Haematology Department, Royal Perth Hospital, Perth, Australia

  • Haematology at Peter MacCallum Cancer Centre and The Royal Melbourne Hospital,Melbourne, VIC,Australie

  • Haematology, Westmead Hospital, Sydney, Australia

  • Haematology Department, Royal Perth Hospital, Perth, Australia

  • Biostatistics Platform,Monash University,Melbourne,Австралия

  • Haematology,Auckland City Hospital,Auckland,Nova Zelândia

  • Haematology, Westmead Hospital, Sydney, Australia

  • Clinical Haematology,Alfred Health,Melbourne,Australien

  • Haematology,Auckland City Hospital,Auckland,Nova Zelândia

  • Pharmacology, St Vincent's Health Network, Sydney, Australia

  • Haematology,Wellington Blood and Cancer Centre,Wellington,Neuseeland

  • Infectious Diseases,Alfred Health,Melbourne,Австралия

  • Haematology,Austin Hospital,Melbourne,Австралия

  • Clinical Haematology,Alfred Health,Melbourne,Australien

  • Haematology,Wellington Blood and Cancer Centre,Wellington,Neuseeland

  • Rheumatology, Austin Health, Melbourne, Australia

  • Medicine,Fred Hutch ,Seattle,États-unis

  • Haematology at Peter MacCallum Cancer Centre and The Royal Melbourne Hospital,Melbourne, VIC,Australie

  • Centre for Health Technologies, University of Technology Sydney, Sydney, Australia.

  • Centre for Health Technologies, University of Technology Sydney, Sydney, Australia.

  • Haematology, Alfred Health, Melbourne, Australia

  • Haematology,Wellington Blood and Cancer Centre,Wellington,Neuseeland

  • Haematology,Auckland City Hospital,Auckland,Nova Zelândia

  • Haematology,Auckland City Hospital,Auckland,Nova Zelândia

  • Haematology, Westmead Hospital, Sydney, Australia

  • Infectious Diseases, Alfred Hospital, Melbourne, Australia

  • Haematology,Auckland City Hospital,Auckland,Новая Зеландия

  • Haematology Department, Royal Perth Hospital, Perth, Australia

Locations

  • United States

  • Australia

  • United Kingdom

  • New Zealand

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Blood/haematological Diseases

  • Autoimmune (AI)

  • Oncology (ONC)

Disease

  • Acute Leukemia

  • Myelodysplastic Syndrome

  • Lymphomas

  • Graft-versus-host disease

Biomarkers

  • Soluble Complement 5b-9

  • Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Epsilon

Drug/Treatment

  • Cyclophosphamide

  • Cyclophosphamide Injection

  • fludarabine tablet

  • Mibefradil

Outcome

  • N/A

Study Design

  • Randomized

Phase

  • N/A

Study Id's

  • ACTRN12618000505202

Sponsors

  • N/A

Result

  • N/A

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