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S217 : PRELIMINARY ANALYSIS OF THE PHASE II STUDY USING TOLINAPANT (ASTX660) MONOTHERAPY IN 98 PERIPHERAL T-CELL LYMPHOMA AND 51 CUTANEOUS T-CELL LYMPHOMA SUBJECTS WITH RELAPSED REFRACTORY DISEASE.

Researchers

Presenter

  • Jean-Marie Michot

Principal Investigators

  • Amitkumar Mehta

  • Felipe Samaniego

  • Emmanuel Bachy

  • Pier Luigi Zinzani

  • Anca Prica

  • Vincent Ribrag

  • Nina Wagner-Johnston

  • Dima El-Sharkawi

  • Ryan Wilcox

  • Martin Sims

  • Jason A Taylor

  • Francine Foss

Medical Centers

  • Cambridge University Hospitals NHS Foundation Trust

  • University of Michigan Medical School, Ann Arbor, MI

  • Hematology Department,Lyon Sud Hospital,Lyon,France

  • Hematology Department,Lyon Sud Hospital,Lyon,France

  • Johns Hopkins University, The Sidney Kimmel Comprehensive Cancer Center,Baltimore,Stati Uniti

  • University of Virginia,Charlottesville,Verenigde Staten

  • University of Virginia, VA.

  • The Royal Marsden NHS Foundation Trust,Surrey,Royaume-uni

  • University of Virginia,Charlottesville,États-unis

  • Astex Pharmaceuticals Inc.,Pleasanton,United States

  • Medicine,University of Michigan,Ann Arbor,Vereinigte Staaten

  • Oxford University Hospitals NHS Trust,Oxford,Vereinigtes Königreich

  • Institute of Hematology,L. and A. Seràgnoli,Bo

  • University of Texas MD Anderson Cancer Center, Houston, Texas, United States

  • Institute of Hematology "L. e A. Seràgnoli",Bologna,Italie

  • The University of Texas MD Anderson Cancer Canter, Houston, TX

  • University of Michigan Medical School, Ann Arbor, MI

  • University of Alabama at Birmingham, Birmingham, Alabama, United States

  • The University of Texas MD Anderson Cancer Canter, Houston, TX

  • Pharmacology,University of Michigan Medical School,Ann Arbor,Estados Unidos

  • The University of Texas MD Anderson Cancer...

  • Astex Pharmaceuticals, Inc.,Pleasanton,États-unis

  • Institute of Hematology "L. e A. Seràgnoli",Bologna,Italie

  • Astex Pharmaceuticals Inc.,Pleasanton,United States

  • Neurology,University of Alabama at Birmingham,Birmingham, AL,Vereinigte Staaten

  • Yale Cancer Center,New Haven,Estados Unidos

  • Yale Cancer Center,New Haven,Verenigde Staten

  • University of Michigan Medical School, Ann Arbor, MI

  • Astex Pharmaceuticals,Cambridge,Reino Unido

  • Neurology,University of Alabama at Birmingham,Birmingham, AL,Vereinigte Staaten

  • Oxford University Hospitals NHS Foundation Trust Oxford UK

  • Astex Pharmaceuticals,Cambridge,Royaume-uni

  • Astex Pharmaceuticals, Inc.,Pleasanton,États-unis

  • Astex Pharmaceuticals Inc.,Pleasanton,United States

  • University of Virginia,Charlottesville,États-unis

  • Astex Pharmaceuticals, Inc.,Pleasanton,États-unis

  • The University of Texas MD Anderson Cancer Canter, Houston, TX

  • Department of Hematology,Institut Gustave Roussy,Villejuif,Francia

  • Institute of Hematology "L. e A. Seràgnoli",Bologna,Italie

  • Princess

  • The Royal Marsden NHS Foundation Trust,Surrey,Royaume-uni

  • DMPK,Astex Pharmaceuticals Limited,Cambridge,Verenigd Koninkrijk

  • Johns Hopkins University, The Sidney Kimmel Comprehensive Cancer Center,Baltimore,Stati Uniti

  • University of Virginia, Charlottesville, Virginia, United States

  • University of Alabama at Birmi

  • Astex Pharmaceuticals,Cambridge,Reino Unido

  • Royal Marsden NHS Foundation Trust,Sutton,Verenigd Koninkrijk

  • Department of Medical Oncology - Institut Gustave Roussy, Villejuif, France

  • The Royal Marsden NHS Foundation Trust,Surrey,Royaume-uni

  • Yale Cancer Center,New Haven,États-unis

  • Department of Hematology,Institut Gustave Roussy,Villejuif,Francia

  • University of Michigan, MI.

  • University of Virginia,Charlottesville,Verenigde Staten

  • Yale Cancer Center New Haven CT United States

  • Princess Margaret Cancer Center, Toronto, ON, Canada

  • Johns Hopkins Un

  • Hematology Department,Lyon Sud Hospital,Lyon,France

  • Hematology Department,Lyon Sud Hospital,Lyon,France

  • Hematology Department,Lyon Sud Hospital,Lyon,France

  • Institute of Hematology "L. e A. Seràgnoli",Bologna,Italie

  • Oxford University Hospitals NHS Foundation Trust Oxford UK

  • DMPK,Astex Pharmaceuticals Limited,Cambridge,Vereinigtes Königreich

  • Yale Cancer Center,New Haven,Verenigde Staten

  • Medicine,University of Michigan,Ann Arbor,Vereinigte Staaten

  • University of Alabama at Birmingham, Birmingham, AL

  • Johns Hopkins University, The Sidney Kimmel Comprehensive Cancer Center,Baltimore,Stati Uniti

  • Royal Marsden NHS Foundation Trust,Sutton,Verenigd Koninkrijk

  • University of Alabama at Birmingham, Birmingham, AL

  • Astex Pharmaceutical, Inc., Cambridge, United Kingdom.

  • Yale Cancer Center, New Haven, CT

  • University of Alabama at Birmingham,Birmingham, AL,Estados Unidos

  • Institute of Hematology "L. e A. Seràgnoli",Bologna,Italie

  • Astex Pharmace

  • The Royal Marsden Hospital NHS Foundation Trust, London & Surrey, United Kingdom

  • Hematology Department,

  • Department of Hematology,Institut Gustave Roussy,Villejuif,Francia

  • Princess Margaret Cancer Center, Toronto, ON, Canada

  • Princess Margaret Cancer Center, Toronto, ON, Canada

  • Department of Leukemia,University of Texas MD Anderson Cancer Center,Houston,Vereinigte Staaten

  • Oxford University Hospitals NHS Trust, Oxford, United Kingdom

  • Johns Hopkins University, The Sidney Kimmel Comprehensive Cancer Center,Baltimore,Stati Uniti

  • Oxford University Hospitals NHS Foundation Trust Oxford UK

  • The Royal Marsden NHS Foundati

  • University of Virginia,Charlottesville,États-unis

  • Astex Pharmaceuticals,Cambridge,Соединённое Королевство

  • Yale Cancer Center,New Haven,Stati Uniti

Locations

  • France

  • United States

  • Italy

  • Sierra Leone

  • Canada

  • United Kingdom

  • India

  • South Africa

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Peripheral T-cell lymphoma

  • Cutaneous T-cell lymphoma

Biomarkers

  • N/A

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • Open Label

  • Single Arm

Phase

  • II

Study Id's

  • NCT02503423

Sponsors

  • N/A

Result

  • N/A

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