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P1041 : IMPACT OF FEDRATINIB ON SPLEEN VOLUME AND MYELOFIBROSIS SYMPTOMS IN PATIENTS WITH SUBSTANTIAL SPLENOMEGALY: POST HOC ANALYSES FROM THE JAKARTA AND JAKARTA2 TRIALS

Researchers

Presenter

  • Jean-Jacques Kiladjian

Principal Investigators

  • Ayalew Tefferi

  • Francesco Passamonti

  • Alessandro Vannucchi

  • Moshe Talpaz

  • Francisco Cervantes

  • Claire N. Harrison

  • Ruben A. Mesa

  • John Mascarenhas

  • Nicolaas Schaap

  • Srdan Verstovsek

  • Timothy Devos

  • Shelonitda Rose

  • Jun Zhang

  • Oumar Sy

  • Animesh Pardanani

Medical Centers

  • University of Michigan Comprehensive Cancer Center, Ann Arbor, MI

  • Bristol Myers Squibbs,Princeton,Vereinigte Staaten

  • Tisch Cancer Institute,Icahn School of Medicine at Mount Sinai,New York,Vereinigte Staaten

  • Université de Paris, INSERM,Paris,Francia

  • Radboud University Medic

  • Radboud University Medical Centre,Nijmegen,Paesi Bassi

  • CRIMM, University of Florence, AOU Careggi,Florence,Italie

  • Guy's and St Thomas' Hospital,London,Reino Unido

  • CRIMM, University of Florence, AOU Careggi,Florence,Italie

  • Université de Paris, INSERM,Paris,Francia

  • Guy's and St Thomas' Hospital,London,Reino Unido

  • University Hospitals Leuven and Laboratory of Molecular Immunology (Rega Institute), KU Leuven,Leuven,Belgio

  • University of Insubria,Varese,Italia

  • Bristol Myers Squibb,Princeton,USA

  • Université de Paris,Paris,Frankreich

  • University of Michigan Comprehensive Cancer Center,Ann Arbor, MI,Vereinigte Staaten

  • The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY

  • CRIMM, University of Florence, AOU Careggi,Florence,Italie

  • CRIMM, University of Florence, AOU Careggi,Florence,Italie

  • University of Texas MD Anderson Cancer Center, Houston, Texas, United States

  • Mayo Clinic of Rochester,Rochester,Estados Unidos

  • Hospital Clinic i Provincial de Barcelona, Barcelona, Spain

  • CRIMM, University of Florence, AOU Careggi,Florence,Italie

  • The University of Texas MD Anderson Cancer Canter, Houston, TX

  • Radboud University Medical Center, Njmegen, Netherlands

  • The University of Texas MD Anderson Cancer Canter, Houston, TX

  • The University of Texas MD Anderson Cancer...

  • University of Insubria,Varese,Italia

  • Bristol Myers Squibb,Princeton, NJ,Estados Unidos

  • Bristol Myers Squibbs,Princeton,Vereinigte Staaten

  • Mayo Clinic of Rochester,Rochester,Estados Unidos

  • May

  • Guy's and St Thomas' Hospital,London,Vereinigtes Königreich

  • Université de Paris,Paris,Frankreich

  • Bristol Myers Squibb,Princeton, NJ,Estados Unidos

  • Hospital Clinic i Provincial de Barcelona, Barcelona, Spain

  • Mays Cancer Center at UT Health San Antonio MD Anderson Cencer Center,San Antonio, TX,Stati Uniti

  • The University of Texas MD Anderson Cancer Canter, Houston, TX

  • The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY

  • Radboud University Medical Centre,Nijmegen,Paesi Bassi

  • University of Michigan Comprehensive Cancer Center, Ann Arbor, MI

  • Mays Cancer Center at UT Health San Antonio MD Anderson Cencer Center,San Antonio, TX,Stati Uniti

  • Tisch Cancer Institute, Icahn School of Medicine at

  • University Hospitals Leuven and Laboratory of Molecular Immunology (Rega

  • University Hospitals Leuven and Laboratory of Molecular Immunology (Rega Institute), KU Leuven,Leuven,Belgio

  • Guy's and St Thomas' Hospital,London,Vereinigtes Königreich

  • Mays Cancer Institute at UT Health San Antonio MD Anderson,San Antonio,United States

  • Mays Cancer Cent

  • University of Insubria,Varese,Italien

  • University of Michigan Comprehensive Cancer Center, Ann Arbor, MI

  • Hematology,Mayo Clinic Rochester,Rochester,Verenigde Staten

  • University of Michigan Comprehensive Cancer Center, Ann Arbor, MI

  • Radboud University Medical Centre, Nijmegen, Israel

  • Hospital Clinic i Provincial de Barcelona, Barcelona, Spain

  • University of Michigan, MI.

  • University of Insubria,Varese,Италия

  • Bristol Myers Squibb,Summit, NJ,Stati Uniti

  • Radboud University Medical Centre, Nijmegen, Israel

  • University of Insubria,Varese,Italia

  • Mays Cancer Center at UT Health San Antonio MD Anderson Cencer Center,San Antonio, TX,Stati Uniti

  • CRIMM, University of Florence, AOU Careggi,Florence,Italie

  • Hematology,Mayo Clinic Rochester,Rochester,Verenigde Staten

  • Radboud University Medical Center, Njmegen, Netherlands

  • Radboud University Medical Center, Njmegen, Netherlands

  • The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY

  • Guy's and St Thomas' Hospital,London,Royaume-uni

  • Guy's And St Thomas NHS Foundation Trust, London, United Kingdom

  • Univ. of Insubria, Varese, Italy

  • Guys and St ThomasHospital, London, UK

  • Mayo Clinic of Rochester,Rochester,Estados Unidos

  • Hospital Clinic i Provincial de Barcelona, Barcelona, Spain

  • Hospital Clinic i Provincial de Barcelona, Barcelona, Spain

  • Hospital Clinic i Provincial de Barcelona, Barcelona, Spain

  • Hopital Saint-Louis,

  • University of Insubria,Varese,Italia

  • Department of Leukemia,University of Texas MD Anderson Cancer Center,Houston,Vereinigte Staaten

  • Hospital Clinic i Provincial de Barcelona, Barcelona, Spain

  • Bristol Meyers Squibb,Princeton,United States

  • University Hospitals Leuven and Laboratory of Molecular Immunology (Rega Institute), KU Leuven,Leuven,Belgio

  • Hematology,Mayo Clinic Rochester,Rochester,Verenigde Staten

Locations

  • France

  • United States

  • Italy

  • Venezuela

  • Spain

  • United Kingdom

  • Netherlands

  • Belgium

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Myelofibrosis

Biomarkers

  • Janus kinase

Drug/Treatment

  • Fedratinib

Outcome

  • N/A

Study Design

  • Placebo Control

Phase

  • III

Study Id's

  • NCT01437787

  • NCT01523171

Sponsors

  • N/A

Result

  • N/A

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