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POS0861 (2021) : EFFECTIVENESS AND SAFETY OF TOCILIZUMAB IN PATIENTS WITH SYSTEMIC SCLEROSIS: A PROPENSITY SCORE CONTROL MATCHED OBSERVATIONAL STUDY OF THE EUSTAR COHORT

Researchers

Presenter

  • S. Kuster

Principal Investigators

  • C. Bruni

  • F. Iannone

  • S. Vettori

  • E. Siegert

  • S. Rednic

  • V. Codullo

  • P. Air

  • Y. Braun-Moscovici

  • N. Hunzelmann

  • M. J. Salvador

  • V. Riccieri

  • A. M. Gheorghiu

  • J. J. Alegre Sancho

  • K. Romanowska-Prochnicka

  • I. Castellv

  • I. Koetter

  • M. E. Truchetet

  • F. J. Lpez-Longo

  • P. Novikov

  • A. Giollo

  • Y. Shirai

  • L. Belloli

  • E. Zanatta

  • E. Hachulla

  • V. Smith

  • C. Denton

  • R. Ionescu

  • T. Schmeiser

  • J. H. W. Distler

  • A. Gabrielli

  • A. M. Hoffmann-Vold

  • M. Kuwana

  • Y. Allanore

  • O. Distler

Medical Centers

  • University Hospital Zürich, University of Zurich, Rheumatology, Zürich, Switzerland

  • University of Zurich, Department of Biostatistics at Epidemiology, Biostatistics and Prevention Institute, Zurich, Switzerland

  • University of Florence, Histology & Embryology Unit, Department of Experimental and Clinical Medicine, Florence, Italy

  • GISEA, Univ Hospital of Bari, Bari, Italy

  • University of Campania ‘Luigi Vanvitelli’, Department of Precision Medicine, Naples, Italy

  • Charite Universitatsmedizin der HU-Berlin, Department of Rheumatology and Clinical Immunology, Berlin, Germany

  • University of Medicine & Pharmacy “Iuliu Hatieganu” Cluj, Clinica Reumatologie, Cluj Napoca, Romania

  • University of Pavia, IRCCS Policlinico S. Matteo Foundation, Department of rheumatology, Pavia, Italy

  • University of Brecsia, ASST Spedali Civili of Brescia, Rheumatology and Clinical Immunology, Brescia, Italy

  • Rambam Health Care Campus, Rappaport Faculty of Medicine, Technion, B. Shine Rheumatology Unit, Hailfa, Israel

  • Universtätsklinikum Köln, Universitätshautklinik Köln, Köln, Germany

  • University of Coimbra, University Hospitals, Department of Rheumatology, Coimbra, Portugal

  • Sapienza University, Internal Medicine and Medical Specialties, Rome, Italy

  • Ion Cantacuzino Clinical Hospital, Department of Internal Medicine and Rheumatology Clinic, Bucharest, Romania

  • University of Valencia, University Hospital Dr. Peset, Department of Rheumatology, Valencia, Spain

  • Institute of Rheumatology, Department of Connective Tissue Disease, Warsaw, Switzerland

  • Hospital Universitari de la Santa Creu i Sant Pau & Dos de Maig, Barcelona, Spain

  • Asklepios Clinic Altona, Medical Department 4, Rheumatology, Immunology, Nephrology, Hamburg, Germany

  • National Reference Center for Systemic Autoimmune Rare Diseases, Hopital Pellegrin, Department of Rheumatology, Bordeaux, France

  • Hospital General Universitario Gregorio Maranon, Department of Rheumatology, Madrid, Spain

  • I.M. Sechenov First Moscow State Medical University, Clinic of Nephrology, Internal and Occupational Diseases, Department of Nephrology, Moscow, Russian Federation

  • University of Verona, Rheumatology Unit, Department of Medicine, Verona, Italy

  • Nippon Medical School Hospital, Allergy and Rheumatology, Tokyo, Japan

  • Niguarda Ca’ Granda Hospital, Rheumatology Unit, Milano, Italy

  • University of Pisa, Unit of Endocrinology, Department of Clinical and Experimental Medicine, Pisa, Italy

  • Referral Centre for Rare Systemic Auto-immune Diseases for North and North-West of France, University of Lille, Department of Internal Medicine, Claude Huriez Hospital, Lille, France

  • University of Ghent, Department of Rheumatology, Ghent, Belgium

  • Royal Free and University College London Medical School, Royal Free Campus, Centre for Rheumatology, London, United Kingdom

  • University of Medicine and Pharmacy, Department of Rheumatology - St. Maria Hospital, Carol Davila, Bucharest, Romania

  • Krankenhaus St. Josef, Innere Medizin und Rheumatologie, Wuppertal-Elberfeld, Germany

  • Universitätsklinikum Erlangen, Department of Internal Medicine 3, Erlangen, Germany

  • Istituto di Clinica Medica Generale, Università Politecnica delle Marche Polo Didattico, Ematologia ed Immunologia Clinica, Ancona, Italy

  • Rikshospitalet University Hospital, Department of Rheumatology, Oslo, Norway

  • Cochin Hospital, APHP, Paris Descartes University, Rheumatology A Department, Paris, France

Locations

  • Switzerland

  • Italy

  • Germany

  • Romania

  • Israel

  • Portugal

  • Spain

  • France

  • Russia

  • Japan

  • Belgium

  • United Kingdom

  • Norway

Companies

  • N/A

Study Components

Therapeutic Area

  • Central Nervous System (CNS)

  • Autoimmune (AI)

  • Genetic Disorder

Disease

  • Scleroderma

  • Mental retardation, X-linked, syndromic, 15

Biomarkers

  • Albumin/creatinine

Drug/Treatment

  • Tocilizumab

Outcome

  • N/A

Study Design

  • Observational

  • Cohort

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • Boehringer Ingelheim

Result

  • N/A

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