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OP0190 (2022) : COMPREHENSIVE GENETIC AND FUNCTIONAL ANALYSES OF Fc GAMMA RECEPTORS EXPLAIN RESPONSE TO RITUXIMAB THERAPY FOR AUTOIMMUNE RHEUMATIC DISEASES

Researchers

Presenter

  • M. Y. MD Yusof

Principal Investigators

  • V. Davies

  • D. Wild

  • M. Morgan

  • J. Taylor

  • Y. El-Sherbiny

  • D. Morris

  • L. Liu

  • A. Rawstron

  • M. H. Buch

  • D. Plant

  • H. Cordell

  • J. Isaacs

  • I. N. Bruce

  • P. Emery

  • A. Barton

  • T. Vyse

  • J. Barrett

  • E. Vital

  • A. Morgan

Medical Centers

  • University of Leeds, Leeds Institue of Rheumatic and Musculoskeletal Medicine, Leeds, United Kingdom

  • Leeds Teaching Hospitals NHS Trust and NIHR Musculoskeletal Biomedical Research Unit, Leeds, United Kingdom

  • University of Leeds, Leeds Institute of Cardiovascular and Metabolic Medicine, Leeds, United Kingdom

  • University of Cambridge, Cancer Research UK Cambridge Institute, Cambridge, United Kingdom

  • Nottingham Trent University, Department of Biosciences, Nottingham, United Kingdom

  • King’s College London, Department of Medical & Molecular Genetics, London, United Kingdom

  • Leeds Teaching Hospitals NHS Trust, Haematological Malignancy Diagnostic Service, Leeds, United Kingdom

  • School of Biological Sciences The University of Manchester, Division of Musculoskeletal and Dermatological Sciences, Manchester, United Kingdom

  • Newcastle University, Population Health Sciences Institute, Newcastle Upon Tyne, United Kingdom

  • Newcastle University, Translational and Clinical Research Institute, Newcastle Upon Tyne, United Kingdom

  • Leeds Teaching Hospitals NHS Trust, NIHR Leeds Medtech and In Vitro Diagnostics Co-operative, Leeds, United Kingdom

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • N/A

Disease

  • N/A

Biomarkers

  • Cluster of Differentiation 107 Antigen-Like Family Member A

  • Fc gamma RIIIa

Drug/Treatment

  • Rituximab

Outcome

  • N/A

Study Design

  • Prospective

  • Cohort

Phase

  • N/A

Study Id's

  • N/A

Sponsors

  • Roche Holding AG

Result

  • N/A

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