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AB0750 (2022) : Back pain and morning stiffness as mediators of tofacitinib treatment effect on fatigue in patients with ankylosing spondylitis: a mediation analysis

Researchers

Presenter

  • L. E. Kristensen

Principal Investigators

  • P. C. Taylor

  • V. Navarro-Compn

  • M. Magrey

  • J. C. Cappelleri

  • A. G. Bushmakin

  • A. Yndestad

  • O. Dina

Medical Centers

  • Copenhagen University Hospital, Bispebjerg and Frederiksberg, The Parker Institute, Copenhagen, Denmark

  • University of Oxford Botnar Research Centre, Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Oxford, United Kingdom

  • University Hospital La Paz, Madrid, Spain

  • Case Western Reserve University, Division of Rheumatology, Cleveland, OH, United States of America

  • Pfizer Inc, Inflammation and Immunology, Peapack, NJ, United States of America

  • Pfizer Inc, Inflammation and Immunology, Oslo, Norway

  • Pfizer Inc, Inflammation and Immunology, Peapack, NJ, United States of America

Locations

  • Denmark

  • United Kingdom

  • Spain

  • United States

  • Norway

Companies

  • N/A

Study Components

Therapeutic Area

  • Autoimmune (AI)

  • Musculoskeletal

Disease

  • Ankylosing spondylitis

Biomarkers

  • N/A

Drug/Treatment

  • Tasocitinib

Outcome

  • N/A


Study Design

  • N/A

Phase

  • III

Study Id's

  • NCT01786668

  • NCT03502616

Sponsors

  • Pfizer

Result

  • N/A