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3504 : Oral maintenance capecitabine versus active monitoring for patients with metastatic colorectal cancer (mCRC) who are stable or responding after 16 weeks of first-line treatment: Results from the randomized FOCUS4-N trial.

Researchers

Presenter

  • Richard Adams

Principal Investigators

  • David Fisher

  • Janet Graham

  • Jenny F. Seligmann

  • Matthew Seymour

  • Richard S. Kaplan

  • Emma Yates

  • Susan D Richman

  • Philip Quirke

  • Rachel Butler

  • Ewan Brown

  • Stephen Falk

  • Fiona Jane Collinson

  • Richard H. Wilson

  • Louise C. Brown

  • Tim Maughan

Medical Centers

  • Cardiff University and Velindre Cancer Centre, Cardiff, United Kingdom

  • Kings College London, London, United Kingdom

  • Beatson West of Scotland Cancer Centre, Glasgow, United Kingdom

  • University of Leeds, Leeds, United Kingdom

  • Gastrointestinal Cancer Research Unit, Cookridge Hospital, Leeds, United Kingdom

  • Medical Research Council Clinical Trials Unit at University College London, London, United Kingdom

  • MRC Clinical Trials Unit, UCL, London, United Kingdom

  • Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, United Kingdom

  • SW Genomics Laboratory Hub, Bristol, United Kingdom

  • Western General Hospital, Edinburgh, United Kingdom

  • Bristol Oncology, Bristol, United Kingdom

  • St James University Hospital, Felliscliffe Harrogate, United Kingdom

  • Institute of Cancer Science, University of Glasgow, Glasgow, United Kingdom

  • Headington, Oxford, United Kingdom

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Gastroenterology (GU)

Disease

  • Colorectal Cancer

Biomarkers

  • B-Raf proto-oncogene, serine/threonine kinase

  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

  • Tumor protein p53

  • Microsatellite instability

Drug/Treatment

  • Capecitabine

  • TP53

Outcome

  • N/A

Study Design

  • Randomized

Phase

  • N/A

Study Id's

  • ISRCTN90061546

Sponsors

  • N/A

Result

  • N/A

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