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11536 : Intra-patient dose escalation (IPDE) of ripretinib after disease progression in patients with advanced gastrointestinal stromal tumor (GIST): Analyses from the phase 3 INVICTUS study.

Researchers

Presenter

  • John Raymond Zalcberg

Principal Investigators

  • Suzanne George

  • Sebastian Bauer

  • Patrick Schoffski

  • Cesar Serrano

  • Robin Lewis Jones

  • Hans Gelderblom

  • Steven Attia

  • Gina Z. D'Amato

  • Ping Chi

  • Peter Reichardt

  • Neeta Somaiah

  • Julie Nicole Meade

  • VIENNA Lynn REICHERT

  • Kelvin Shi

  • Matthew L. Sherman

  • Rodrigo Ruiz-Soto

  • Margaret von Mehren

  • Jean-Yves Blay

Medical Centers

  • Deakin University, Melbourne, Australia

  • OHSU Knight Cancer Institute, Portland, OR, Dana-Farber Cancer Institute, Boston, MA

  • West German Cancer Center, Essen, Germany

  • University Hospitals Leuven and KU Leuven, Leuven, Belgium

  • Vall d'Hebron Institute of Oncology, Barcelona, Spain

  • Royal Marsden Hospital and Institute of Cancer Research, London, United Kingdom

  • Leiden University Medical Centre, Leiden, Netherlands

  • Mayo Clinic, Jacksonville, FL, Sylvester Comprehensive Cancer Center, University of Miami Health System, Miami, FL, Memorial Sloan Kettering Cancer Center, New York, NY, Sarcoma Center, Helios Klinikum Berlin Buch, Berlin, Germany

  • The University of Texas MD Anderson Cancer Canter, Houston, TX

  • Deciphera Pharmaceuticals, Inc, Waltham, MA

  • Fox Chase Cancer Center, Philadelphia, PA, Centre Léon Bérard, Lyon, France

Locations

  • Australia

  • Germany

  • Belgium

  • Spain

  • United Kingdom

  • Netherlands

  • France

Companies

  • Deciphera Pharmaceut

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Gastrointestinal stromal tumor

Biomarkers

  • N/A

Drug/Treatment

  • DCC-2618

Outcome

  • N/A

Study Design

  • Randomized

  • Placebo Control

  • Double Blind/Blinded

  • Dose Escalation

Phase

  • III

Study Id's

  • NCT03353753

Sponsors

  • N/A

Result

  • N/A

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