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4004 : Neo-AEGIS (Neoadjuvant trial in Adenocarcinoma of the Esophagus and Esophago-Gastric Junction International Study): Preliminary results of phase III RCT of CROSS versus perioperative chemotherapy (Modified MAGIC or FLOT protocol). (NCT01726452).

Researchers

Presenter

  • John V. Reynolds

Principal Investigators

  • Brian O'Neill

  • Maeve Aine Lowery

  • Lene Baeksgaard

  • Thomas Crosby

  • Moya Cunningham

  • Sinead Cuffe

  • Gareth Owen Griffiths

  • Rajarshi Roy

  • Stephen Falk

  • George Hanna

  • Frederick R. Bartlett

  • Imelda Parker

  • Alberto Alvarez-Iglesias

  • Magnus Nilsson

  • Guillaume Piessen

  • Signe Risum

  • Narayanasamy Ravi

  • Raymond S. McDermott

Medical Centers

  • Cancer Trials Ireland and St James's Hospital, Dublin, Ireland

  • Royal Surrey County Hospital NHS Foundation Trust, Guildford, United Kingdom

  • St Lukes Radiation Oncology Network, Dublin, Ireland

  • Saint James's Hospital, Dublin, Ireland

  • Rigshospitalet, Copenhagen, Denmark

  • Velindre NHS Trust, Cardiff, United Kingdom

  • St Lukes Radiation Oncology Network, Dublin, Ireland

  • Saint James's Hospital, Dublin, Ireland

  • Southampton Clinical Trials Unit,University of Southampton, Southampton, United Kingdom

  • Hull University Teaching Hospitals, Hull, United Kingdom

  • University Hospitals Bristol NHS Foundation Trust, Wells Somerset, United Kingdom

  • Hammersmith Hospital, Imperial College, London, United Kingdom

  • Portsmouth Hospital NHS Trust, Portsmouth, United Kingdom

  • Cancer Trials Ireland

  • Dublin, Ireland

  • HRB Clinical Research Facility, Galway, Ireland

  • Division of Surgery, CLINTEC, Karolinska Institutet and Department of Upper Abdominal Diseases, Karolinska University Hospital, Stockholm, Sweden

  • Claude Huriez Hospital, Lille, France

  • Rigshospitalet, Copenhagen, Denmark

  • Saint James's Hospital, Dublin, Ireland

  • Dublin, Dublin, Ireland

Locations

  • Ireland

  • United Kingdom

  • Denmark

  • Sweden

  • France

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Esophageal Cancer

Biomarkers

  • N/A

Drug/Treatment

  • Capecitabine

  • Carboplatin

  • Oxaliplatin

  • Epirubicin

  • leucovorin

  • Paclitaxel

  • Docetaxel

  • Cisplatin

  • Hydroxyzine

  • Adrucil injection

Outcome

  • N/A

Study Design

  • Superiority

  • Non Inferiority

  • Multinational

Phase

  • III

Study Id's

  • NCT01726452

Sponsors

  • N/A

Result

  • N/A

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