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TPS3145 : Phase I trial of acoustic cluster therapy (ACT) with chemotherapy in patients with liver metastases of gastrointestinal origin (ACTIVATE study).

Researchers

Presenter

  • Udai Banerji

Principal Investigators

  • Crescens Diane Tiu

  • Andra Curcean

  • Sumita Gurung

  • Mark O'Leary

  • Nigel Bush

  • Spiros Kotopoulis

  • Andrew Healey

  • Svein Kvle

  • Hilary Hilary McElwaine-Johnn

  • Jeff Bamber

  • Robert Miller

  • Per Sontum

  • Sarah Arbe-Barnes

  • Nina Tunariu

Medical Centers

  • The Institute of Cancer Research & The Royal Marsden, London, Spain

  • The Royal Marsden Hospital NHS Foundation Trust, London & Surrey, United Kingdom

  • The Institute of Cancer Research, Sutton, United Kingdom

  • EXACT Therapeutics AS, Oslo, Norway

  • EXACT Therapeutics AS, Oslo, Norway

  • The Institute of Cancer Research, The Royal Marsden NHS Foundation Trust, Sutton, United Kingdom

Locations

  • United Kingdom

  • Norway

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Pancreas ductal adenocarcinoma

  • Colorectal Cancer

  • Solid malignancies

  • Secondary liver cancer

Biomarkers

  • N/A

Drug/Treatment

  • Gemcitabine

  • Paclitaxel

  • FOLFIRI

  • Oxaliplatin, 5-fluorouracil and folic acid

Outcome

  • N/A

Study Design

  • Randomized

  • Double Blind/Blinded

  • Open Label

  • Non Randomized

  • Dose Escalation

Phase

  • I

Study Id's

  • NCT04021277

Sponsors

  • N/A

Result

  • N/A

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