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P458 : Safety and Potential Efficacy of Escalating Dose of Ustekinumab in Pediatric Crohn's disease (the SPEED-UP study) - A multi-center study from the paediatric IBD Porto group of ESPGHAN

Researchers

Presenter

  • Yerushalmy-Feler, A

Principal Investigators

  • Martin-de-Carpi, J

  • Kolho, K.L

  • Levine, A

  • Olbjrn, C

  • Granot, M

  • Bramuzzo, M

  • Jonsson Rolandsdotter, H

  • Mouratidou, N

  • Hradsky, O

  • Scarallo, L

  • Matar, M

  • Magen Rimon, R

  • Rinawi, F

  • Shalem, T

  • Najajra, H

  • de Meij, T

  • Aloi, M

  • Velasco Rodrguez-Belvs, M

  • Alvisi, P

  • Schneider, A.M

  • van Rheenen, P

  • Navas-Lpez, V.M

  • Kiparissi, F

  • Barrio, J

  • Turner, D

  • Cohen, S

Medical Centers

  • "Dana-Dwek" Children's Hospital- Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine- Tel Aviv University, Pediatric Gastroenterology Institute, Tel Aviv, Israel

  • Hospital Sant Joan de Deu, Department of Gastroenterology, Hepatology and Pediatric Nutrition, Barcelona, Spain

  • Children's Hospital and University of Helsinki- Helsinki- Finland and Tampere University, Department of Paediatric Gastroenterology, Tampere, Finland

  • Wolfson Medical Center and the Sackler Faculty of Medicine- Tel Aviv University, Pediatric Gastroenterology Unit- PIBD research center, Tel Aviv, Israel

  • Akershus University Hospital, Department of Paediatric and Adolescent Medicine, Lorenskog, Norway

  • Edmond and Lliy Safra Children's Hospital, Pediatric Gastroenterology Unit, Ramat Gan, Israel

  • Institute for Maternal and Child Health-IRCCS "Burlo Garofolo", Gastroenterology- Digestive Endoscopy and Nutrition Unit, Trieste, Italy

  • Department of Clinical Science and Education- Karolinska Institutet, Department of Gastroenterology- Sachs' Children and Youth Hospital, Stockholm, Sweden

  • Karolinska University Hospital, Department of Pediatric Gastroenterology- Hepatology and Nutrition, Stockholm, Sweden

  • Charles University in Prague and General University Hospital in Prague, Department of Psychiatry, First Faculty of Medicine, Prague, Czech Republic

  • Meyer Pediatric Hospital, Gastroenterology and Nutrition unit, Florence, Italy

  • Schneider Children's Medical Center and the Sackler Faculty of Medicine- Tel Aviv University, Institute of Gastroenterology- Nutrition and Liver Diseases-, Tel Aviv, Israel

  • Ruth Children's Hospital of Haifa- Rambam Medical Center- Faculty of Medicine- Technion, Pediatric Gastroenterology and Nutrition Institute, Haifa, Israel

  • Ha'Emek Medical Centre, Paediatrics Gastroenterology Unit, Afula, Israel

  • Shamir Medical Center, The Jecheskiel Sigi Gonczarowski Pediatric Gastroenterology Unit, Zerifin, Israel

  • Shaare Zedek Medical Center, Juliet Keidan Institute of Pediatric Gastroenterology and Nutrition, Jerusalem, Israel

  • Amsterdam University Medical Centre, Department of Pediatric Gastroenterology, Amsterdam, Netherlands Antilles

  • Umberto I Hospital- Sapienza University of Rome, Department of Maternal and Child Health- Pediatric Gastroenterology and Liver Unit-, Rome, Italy

  • Hospital Niño Jesús, Paediatric Gastroenterology- Hepatology and Nutrition, Madrid, Spain

  • Maggiore Hospital, Pediatric Gastroenterology Unit- Department of Pediatrics, Bologna, Italy

  • Paracelsus Medical University, Department of Pediatrics, Salzburg, Austria

  • University Medical Centre Groningen Beatrix Childrens Hospital, Paediatric Gastroenterology, Groningen, Netherlands Antilles

  • Hospital Regional Universitario de Málaga, Pediatric Gastroenterology and Nutrition Unit, Málaga, Spain

  • Great Ormond Street Hospital for Children NHS Foundation Trust- Great Ormond Street, Department of Pediatric Gastroenterology, London, United Kingdom

  • Hospital Universitario de Fuenlabrada, Department of Paediatrics, Madrid, Spain

  • Shaare Zedek Medical Centre, The Hebrew University of Jerusalem, The Juliet Keidan Institute of Paediatric Gastroenterology and Nutrition, Jerusalem, Israel

Locations

  • Israel

  • Spain

  • Finland

  • Norway

  • Italy

  • Sweden

  • Czech Republic

  • Austria

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Infectious Diseases (ID)

  • Gastroenterology (GU)

  • Genetic Disorder

Disease

  • Crohn's disease

  • Inflammatory bowel disease

Biomarkers

  • N/A

Drug/Treatment

  • Ustekinumab

Outcome

  • N/A

Study Design

  • Multicenteric

  • Dose Escalation

Phase

  • N/A

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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