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P009 : Integrin-b7+ cytotoxic MAIT cells are expanded in the colon of Ulcerative Colitis patients, correlate with disease severity and are targeted by vedolizumab therapy.

Researchers

Presenter

  • Hermangild Kottoor

Principal Investigators

  • ibraheim, H

  • Polychronis, P

  • Senthuran, B

  • Jameson, E

  • Samaan, M

  • Irving, P

  • Powell, N

Medical Centers

  • Imperial College London, Department of Metabolism Digestion and Reproduction, London, United Kingdom

  • Guy's And St Thomas NHS Foundation Trust, London, United Kingdom

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Autoimmune (AI)

Disease

  • Ulcerative colitis

Biomarkers

  • Peripheral blood mononuclear cell

  • Cluster of Differentiation 4

  • Cluster of differentiation 8A

  • Granzyme B

  • Interleukin 13

  • Tumor necrosis factor

  • T-cell receptor

Drug/Treatment

  • Entyvio

  • lonomycin

  • IFN-lambda

Outcome

  • N/A

Study Design

  • N/A

Phase

  • N/A

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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