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: A critical epithelial survival axis regulated by MCL-1 maintains thymic function

Researchers

Presenter

  • Reema Jain

Principal Investigators

  • Julie M. Sheridan

  • Antonia Policheni

  • Melanie Heinlein

  • Luke C. Gandolfo

  • Grant Dewson

  • Gordon K. Smyth

  • Stephen N. Sansom

  • Nai Yang Fu

  • Jane E. Visvader

  • Justine D. Mintern

  • Iris Tan

  • Georg Hollnder

  • Andreas Strasser

  • Daniel H.D. Gray

Medical Centers

  • Fred Hutchinson Cancer Res. Ctr.,

  • Walter and Eliza Hall Inst. of Med. Res., Australia

  • University of Oxford, Oxford, United Kingdom

  • Bio21 Molecular Science and Biotechnology Institute, Australia

Locations

  • Australia

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Blood/haematological Diseases

Disease

  • Hematology-oncology disease

  • Lymphocytopenia

  • Solid malignancies

Biomarkers

  • Mitogen-activated protein kinase

  • BCL2 associated X, apoptosis regulator

  • Extracellular signal-regulated kinase

  • MAPK/ERK

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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