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: Combined LC-QTOF-MS urine metabolomics and 18F-NaF PET imaging indicates novel compounds associated with spine osteoarthropathy in the rare disease alkaptonuria

Researchers

Presenter

  • B.P. Norman

Principal Investigators

  • L.F. Taylor

  • A.S. Davison

  • A.M. Milan

  • G.A. Ross

  • N.B. Roberts

  • S. Vinjamuri

  • L.R. Ranganath

  • J.A. Gallagher

Medical Centers

  • Inst. of Ageing & Chronic Disease, Univ. of Liverpool, Liverpool, United Kingdom

  • Liverpool Clinical Lab., Royal Liverpool & Broadgreen Univ. Hosp. NHS Trust, Liverpool, United Kingdom

  • Agilent Technologies UK Ltd, Cheadle, United Kingdom

  • Dept. of Nuclear Med., Royal Liverpool & Broadgreen Univ. Hosp. NHS Trust, Liverpool, United Kingdom

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Genetic Disorder

Disease

  • Alkaptonuria

Biomarkers

  • N/A

Drug/Treatment

  • Nitisinone

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A