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: Polymorphic variants in ALDH1A2 determine the expression level of ALDH1A2 and CYP19A1 in the cartilage of patients undergoing trapeziectomy for severe thumb osteoarthritis

Researchers

Presenter

  • L. Zhu

Principal Investigators

  • A. Chanalaris

  • K. Groves

  • D. Furniss

  • F.E. Watt

  • M. Gardiner

  • T.L. Vincent

Medical Centers

  • Kennedy Institute of Rheumatology, University of Oxford, Oxford, United Kingdom

  • Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Oxford, United Kingdom

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Musculoskeletal

Disease

  • Osteoarthritis

Biomarkers

  • ADAM Metallopeptidase With Thrombospondin Type 1 Motif 5

  • Aldehyde Dehydrogenase 1 Family Member A2

  • C-C Motif Chemokine Ligand 2

  • Aromatase

  • Matrix metalloproteinase 13

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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