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: Disruption of collagen triple helix hydrogen bonding in ochronotic human cartilage in alkaptonuria observed by dynamic nuclear polarisation-enhanced solid-state nuclear magnetic resonance spectroscopy

Researchers

Presenter

  • B.P. Norman

Principal Investigators

  • C. Wing Ying

  • H. Sutherland

  • P.J. Wilson

  • N.B. Roberts

  • M.J. Duer

  • H. Oschkinat

  • L.R. Ranganath

  • J.A. Gallagher

Medical Centers

  • Inst. of Ageing & Chronic Disease, Univ. of Liverpool, Liverpool, United Kingdom

  • Leibniz-Institut fuer Molekulare Pharmakologie (FMP), Berlin, Germany

  • Liverpool Clinical Lab., Royal Liverpool & Broadgreen Univ. Hosp. NHS Trust, Liverpool, United Kingdom

  • Dept. of Chemistry, Univ. of Cambridge, Cambridge, United Kingdom

Locations

  • United Kingdom

  • Germany

Companies

  • N/A

Study Components

Therapeutic Area

  • Genetic Disorder

Disease

  • Alkaptonuria

Biomarkers

  • N/A

Drug/Treatment

  • N/A

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A