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: Inhibition of LRP1 shedding reverses cartilage degradation in osteoarthritis

Researchers

Presenter

  • K. Yamamoto

Principal Investigators

  • C. Scavenius

  • S. Santamaria

  • K.A. Botkjaer

  • J. Dudhia

  • L. Troeberg

  • Y. Itoh

  • G. Murphy

  • J.J. Enghild

  • H. Nagase

Medical Centers

  • MRC/ARUK Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, United Kingdom

  • Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark

  • Centre for Haematology, Imperial Collegel, London, United Kingdom

  • Cancer Research UK Cambridge Institute, University of Cambridge., Cambridge, United Kingdom

  • Dept. of Clinical Sci. and Services, Royal Vet. Coll., Herts, United Kingdom

  • Kennedy Institute of Rheumatology, University of Oxford, Oxford, United Kingdom

Locations

  • United Kingdom

  • Denmark

Companies

  • N/A

Study Components

Therapeutic Area

  • Musculoskeletal

Disease

  • Osteoarthritis

Biomarkers

  • Low-density lipoprotein receptor-related protein 1

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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