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Abstract P70 : SPAK/OSR1 Signaling as a Novel Target for Post-Stroke Oxidative Stress Brain Injury

Researchers

Presenter

  • Jun Wang

Principal Investigators

  • Victoria M Fiesler

  • Gulnaz Begum

  • Mohammad Iqbal H Bhuiyan

  • Shuying Dong

  • Eric Li

  • Kristopher T Kahle

  • Jinwei Zhang

  • Xianming Deng

  • Yan Yin

  • Dandan Sun

Medical Centers

  • Dept of Neurology, Univ of Pittsburgh Sch of Medicine, Pittsburgh, PA

  • Depts of Neurosurgery, Pediatrics and Cellular & Molecular Physiology, Interdepartmental Neuroscience Program and Cntrs for Mendelian Genomics, Yale Sch of Medicine, New Haven, CT

  • Institute of Biomedical and Clinical Sciences, Med Sch, College of Medicine and Health, Univ of Exeter, Exeter, United Kingdom

  • State Key Laboratory of Cellular Stress Biology, Innovation Cntr for Cell Signaling Network, Sch of Life Sciences, Xiamen Univ, Xiamen, China

  • Dept of Neurology, The Second Hosp of Dalian Med Univ, Dalian, China

Locations

  • United States

  • United Kingdom

  • China

Companies

  • N/A

Study Components

Therapeutic Area

  • Central Nervous System (CNS)

  • Cardiovascular (CVS)

  • Genetic Disorder

Disease

  • Ischemia-reperfusion injury

  • Ischemic stroke

  • Stroke

Biomarkers

  • Solute Carrier Family 12 Member 2

Drug/Treatment

  • Hydrogen peroxide

  • Bumetanide

  • Ebselen

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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