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THU0005 : VARIABILITY OF DNA METHYLATION IS A DRIVER OF LYMPHOCYTE DYSREGULATION IN EARLY RHEUMATOID ARTHRITIS.

Researchers

Presenter

  • A. Clark

Principal Investigators

  • N. Naamane

  • N. Nair

  • A. Anderson

  • N. Thalayasingam

  • J. Diboll

  • A. Barton

  • S. Eyre

  • J. D. Isaacs

  • L. Reynard

  • A. Pratt

Medical Centers

  • Newcastle University Clinical and Translational Research Institute, Newcastle upon Tyne, United Kingdom

  • Arthritis Research UK Centre for Genetics and Genomics, University of Manchester, Manchester, United Kingdom

  • NIHR Manchester Musculoskeletal BRC, Manchester University NHS Foundation Trust, Manchester, UNITED KINGDOM

  • Musculoskeletal Directorate, Newcastle upon Tyne Hospitals NHS Trust, Newcastle upon Tyne, UK

  • Newcastle University and AMLo Biosciences Ltd, Newcastle upon Tyne, United Kingdom

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Autoimmune (AI)

Disease

  • Rheumatoid arthritis

Biomarkers

  • Cluster of Differentiation 19

  • Cluster of Differentiation 4

  • DNA methylation

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • Controlled

  • Cohort

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • Pfizer

Result

  • N/A

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