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THU0022 : DIFFERENTIAL DNA METHYLATION AS A PREDICTOR OF TOCILIZUMAB RESPONSE IN RHEUMATOID ARTHRITIS PATIENTS

Researchers

Presenter

  • N. Nair

Principal Investigators

  • D. Plant

  • J. Isaacs

  • A. Morgan

  • K. Hyrich

  • A. Barton

  • A. G. Wilson

Medical Centers

  • The University of Manchester, Versus Arthritis Centre for Genetics and Genomics and Centre for Epidemiology, Manchester, United Kingdom

  • NIHR Manchester Musculoskeletal Biomedical Research Unit, Manchester, United Kingdom

  • Newcastle University, NIHR Newcastle BRC, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, United Kingdom

  • Leeds School of Medicine, University of Leeds and NIHR Leeds BRC, Leeds, United Kingdom

  • University College Dublin School of Biomolecular and Biomedical Science, Dublin, Ireland

Locations

  • United Kingdom

  • Ireland

Companies

  • N/A

Study Components

Therapeutic Area

  • Autoimmune (AI)

Disease

  • Rheumatoid arthritis

Biomarkers

  • DNA methylation

Drug/Treatment

  • Glucocorticoid

  • Tocilizumab

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A