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SAT0350 : A ROLE FOR IL-17A IN THE SUPPRESSION OF SPINAL ENTHESEAL MESENCHYMAL STEM CELL ADIPOGENESIS WHILST SIMULTANEOUSLY FACILITATING OSTEOGENESIS.

Researchers

Presenter

  • T. Russell

Principal Investigators

  • C. Bridgewood

  • A. Khan

  • A. S. Rao

  • P. Loughenbury

  • P. Millner

  • R. Dunsmuir

  • A. Altaie

  • E. Jones

  • D. Mcgonagle

Medical Centers

  • University of Leeds, Leeds Institue of Rheumatic and Musculoskeletal Medicine, Leeds, United Kingdom

  • Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Musculoskeletal

  • Genetic Disorder

Disease

  • Short stature, onychodysplasia, facial dysmorphism, and hypotrichosis

Biomarkers

  • Interleukin 17A

  • Mesenchymal stem cells

  • Tumor necrosis factor

Drug/Treatment

  • N/A

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • Novartis

Result

  • N/A