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: Targeting Macrophage Activation in Hyperhemolysis Syndrome with Novel Use of Tocilizumab

Researchers

Presenter

  • Lauren E Lee

Principal Investigators

  • Bradley W Beeler

  • Aaron T Henderson

  • Brendan C Graham

  • Michael B Osswald

  • Nay Win

  • Andrew P Cap

Medical Centers

  • Otolaryngology, San Antonio Military Medical Center, Ft Sam Houston, TX

  • San Antonio Military Medical Center, Fort Sam Houston, TX

  • Tooting Centre, National Health Service Blood and Transplant, Tooting, United Kingdom

  • Blood Program, US Army Institute of Surgical Research, JBSA FT Sam Houston, TX

Locations

  • United States

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Blood/haematological Diseases

  • Cardiovascular (CVS)

Disease

  • Sickle cell anemia

  • Congestive heart failure

  • Anemia

  • Breast and ovarian cancer syndrome

Biomarkers

  • Polypeptide N-Acetylgalactosaminyltransferase 3

  • Dopamine transporter

  • Ferritin

  • Stearoyl-CoA desaturase

  • Red Blood Cells

Drug/Treatment

  • Methylprednisolone

  • Erythropoietin

  • Cyanocobalamin

  • ILS-969

  • Ascorbic acid

  • Levofloxacin

  • Tocilizumab

  • Interleukin

  • Eculizumab

  • FA-8

  • Rituximab

  • IVIG

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A