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: KIT D816 Mutated / CBF-Negative Acute Myeloid Leukemia (AML): A New Poor-Risk Subtype Associated with Systemic Mastocytosis (SM-AML)

Researchers

Presenter

  • Mohamad Jawhar

Principal Investigators

  • Sebastian Kreil

  • Juliana Schwaab

  • Khalid Shoumariyeh

  • Manja Meggendorfer

  • Lambert L.F. Span

  • Stephan Fuhrmann

  • Nicole Naumann

  • Hans-Peter Horny

  • Karl Sotlar

  • Boris Kubuschok

  • Nikolas von Bubnoff

  • Karsten Spiekermann

  • Michael Heuser

  • Georgia Metzgeroth

  • Alice Fabarius

  • Stefan A Klein

  • Wolf-Karsten Hofmann

  • Hanneke Kluin-Nelemans

  • Torsten Haferlach

  • Hartmut Dhner

  • Nicholas C.P. Cross

  • Wolfgang R. Sperr

  • Peter Valent

  • Andreas Reiter

Medical Centers

  • Department of Hematology and Oncology,University Hospital Mannheim, Heidelberg University,Mannheim,Deutschland

  • Department of Internal Medicine, University Hospital of Ulm, Ulm, Germany

  • Department of Hematology/Oncology and Stem Cell Transplantation, University Medical Center, Freiburg, Germany

  • Munich Leukemia Laboratory, Munich, Germany.

  • University Medical Center, University of Groningen, Groningen, Netherlands

  • Department of Hematology and Oncology,HELIOS Hospital Berlin-Buch,Berlin,Germania

  • Institute of Pathology, Ludwig-Maximilians-University, Munich, Germany

  • Institute of Pathology, Medical University of Graz, Graz, Austria

  • Department of Internal Medicine I, José-Carreras Centrum for Immuno- and Gene Therapy, University of Saarland Medical School, Homburg/Saar, Homburg, Germany

  • Department of Hematology, Oncology and Stem Cell Transplantation, Uniklinik Freiburg, Freiburg, Germany

  • Laboratory for Leukemia Diagnostics,Department of Medicine III, University Hospital, LMU Munich,Munich,Deutschland

  • Dept. Hematology, Hemostaseology, Oncology & Stem Cell Transplantation, Hannover Medical School, Hannover, Germany

  • Department of Hematology and Oncology, University Hospital, Rostock, Germany

  • MLL Muenchner Leukaemie Labor, Muenchen, Germany

  • University Medical Center Ulm, Ulm, Germany

  • University of Southampton, United Kingdom.

  • Department of Internal Medicine I, Division of Hematology and Hemostaseology and Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Vienna, Austria

Locations

  • Germany

  • Netherlands

  • Austria

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Autoimmune (AI)

Disease

  • Acute myelocytic leukemia

  • Mastocytosis

  • Chronic myelomonocytic leukemia

Biomarkers

  • Nucleophosmin 1

  • ETV6-RUNX1

  • Fms related tyrosine kinase 3

  • Isocitrate dehydrogenase 1

  • KIT Proto-Oncogene, Receptor Tyrosine Kinase

  • Tet methylcytosine dioxygenase 2

  • Tumor protein p53

Drug/Treatment

  • TP53

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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