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: Slit-Robo Pathway Is Clinically Relevant and May Represent a Potential Target in Acute Promyelocytic Leukemia

Researchers

Presenter

  • Isabel Weinhuser

Principal Investigators

  • Cesar Ortiz

  • Josiane Lilian Schiavinato

  • Camila Bonaldo

  • Luisa C Koury

  • Virginia Mara De Deus Wagatsuma

  • Raul Antnio Morais Melo

  • Rosane Bittencourt

  • Katia B Pagnano

  • Evandro Maranhao Fagundes

  • Ana Beatriz F. Gloria

  • Fabio R. Kerbauy

  • Maria de Lourdes Chauffaille

  • Ricardo Pasquini

  • Martin S. Tallman

  • Raul Ribeiro

  • Richard Dillon

  • Armand Keating

  • Arnold Ganser

  • Bob Lowenberg

  • Peter Valk

  • Francesco Lo-Coco

  • Miguel A. Sanz

  • Nancy Berliner

  • Antonio R. Lucena-Araujo

  • Eduardo Magalhaes Rego

Medical Centers

  • Center for Cell Based Therapy, University of Sao Paulo, Ribeirao Preto, Brazil

  • Medical School of Ribeirao Preto and Center for Cell Based Therapy, University of São Paulo, Ribeirão Preto, Brazil

  • Division of Hematology, Department of Internal Medicine, Medical School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil

  • Center for Cell Based Therapy, University of Sao Paulo, Ribeirao Preto, Brazil

  • Fundacao Hemocentro, Ribeirao Preto, Brazil

  • Medical School of Ribeirao Preto and Center for Cell Based Therapy, University of São Paulo, Ribeirão Preto, Brazil

  • Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto Medical School, Ribeirao Preto, Brazil

  • UNIVERSIDADE DE PERNAMBUCO / HEMOPE, RECIFE, BRA

  • , University Hospital of the Federal University of Rio Grande do Sul,Porto Alegre,Brasil

  • INCT do Sangue, Hemocentro UNICAMP,University of Campinas, Sao Paulo, Brazil

  • Hematology Division, Federal University of Minas Gerais, Belo Horizonte, Brazil

  • Federal University of Sao Paulo, Sao Paulo, UT

  • Federal University of Sao Paulo (UNIFESP), Sao Paulo, Brazil

  • Hematologia e Hemoterapia, Universidade Federal de Sao Paulo, Sao Paulo, Brazil

  • Hematology Division, Federal University of Paraná, Curitiba, Brazil

  • Lymphoma Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY

  • Department of Oncology and Global Medicine, International Outreach Program, St. Jude Children's Research Hospital, Memphis, TN

  • Kings College London, London, United Kingdom

  • Princess Margaret Cancer Centre, Princess Margaret Hospital, Toronto, ON, Canada

  • Dept. Hematology, Hemostaseology, Oncology & Stem Cell Transplantation, Hannover Medical School, Hannover, Germany

  • Department of Medical Oncology, VU University Medical Center, Amsterdam, Netherlands

  • University of Rome Tor Vergata, Rome, Italy

  • Department of Medicine, Hospital Universitari i Politecnic La Fe and Centro de Investigación Biomédica en Red de Cáncer, University of Valencia and Instituto Carlos III, Madrid, Madrid, Spain

  • Department of Medicine, Brigham and Women's Hospital, Boston, MA

  • Genetics postgraduate program, Biosciences Center, Federal University of Pernambuco, Recife, Brazil

  • Medical School of Ribeirao Preto, USP, Ribeirao Preto, Brazil

  • Division of Hematology, Department of Internal Medicine, University of São Paulo, Ribeirão Preto, Brazil

Locations

  • Brazil

  • United States

  • United Kingdom

  • Canada

  • Germany

  • Netherlands

  • Italy

  • Spain

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Blood/haematological Diseases

Disease

  • Acute promyelocytic leukemia

  • Acute Leukemia

Biomarkers

  • Promyelocytic Leukemia

  • Slit Guidance Ligand 2

Drug/Treatment

  • Tretinoin

Outcome

  • N/A

Study Design

  • Multinational

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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