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: FOXM1 and the NPM-ALK/STAT3 Axis Form a Novel Positive Feedback Loop in Promoting the Oncogenesis of ALK-Positive Anaplastic Large Cell Lymphoma

Researchers

Presenter

  • Peng Wang

Principal Investigators

  • Moinul Haque

  • Jing Li

  • Yung-Hsing Huang

  • Meaad Almowaled

  • Carter Bargar

  • Adam Karpf

  • Will Chen

  • Suzanne Turner

  • Raymond Lai

Medical Centers

  • Division of Rheumatology, Department of Medicine, University of Alberta, Canada, Edmonton, AB, Canada

  • University of Alberta, Edmonton, AB, Canada

  • University of Alberta, Edmonton, AB, Canada

  • Eppley Institute and Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha

  • University of Cambridge, Cambridge, United Kingdom

  • Department of Pathology and Laboratory Medicine, University of Alberta Cross Cancer Institute, Edmonton, CAN

Locations

  • Canada

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Musculoskeletal

  • Genetic Disorder

Disease

  • Lymphomas

  • Short stature, onychodysplasia, facial dysmorphism, and hypotrichosis

Biomarkers

  • Forkhead box M1

  • Insulin-like growth factor 1

  • Interleukin-21

  • Interleukin-9

  • Signal transducer and activator of transcription 3

Drug/Treatment

  • Thiostrepton

  • Crizotinib

  • Mecasermin

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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