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: Subtractive Interaction Proteomics Reveal a Network of Signaling Pathways Activated By an Oncogenic Transcription Factor in High Risk AML

Researchers

Presenter

  • Claudia Chiriches

Principal Investigators

  • Nathalie Guillen

  • Michal Rokicki

  • Carol Guy

  • Afsar Mian

  • Oliver G. Ottmann

  • Martin Ruthardt

Medical Centers

  • Cardiff University, Department of Hematology Division of Cancer and Genetics, Cardiff, United Kingdom

  • Goethe University, Frankfurt, Germany

Locations

  • United Kingdom

  • Germany

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Solid malignancies

Biomarkers

  • Abelson murine leukemia viral oncogene homolog

  • Promyelocytic Leukemia

  • Clusterin

  • cMYC

  • DEK Proto-Oncogene

  • Forkhead Box O1

  • Serine/threonine-protein kinase mTOR

  • Signal transducer and activator of transcription 5

Drug/Treatment

  • NVP-BEZ235

  • dasatinib

  • Imatinib

  • IkT001

  • BEZ-235

  • T-15

Outcome

  • N/A

Study Design

  • Cohort

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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