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: Aging of Bone Marrow Microenvironment Promotes Myeloid Bias of Hematopoietic Progenitors and Is a Target in Age-Related Myeloproliferative Neoplasms

Researchers

Presenter

  • Ya-Hsuan Ho

Principal Investigators

  • Jos Rivera-Torres

  • Justyna Rak

  • Claudia Korn

  • Andrs Garca-Garca

  • Lucia Kubovcakova

  • David Macas

  • Lorena Arranz

  • Cristina Gonzlez-Gomez

  • Monika Wittner

  • Ronny Nienhold

  • Amie K Waller

  • Holly R Foster

  • Carlos Lopez-Otin

  • Randall S Johnson

  • Claus Nerlov

  • William Vainchenker

  • Cedric Ghevaert

  • Fawzia Louache

  • Radek C. Skoda

  • Vicente Andrs

  • Simon Mendez-Ferrer

Medical Centers

  • University of Cambridge, Cambridge, United Kingdom

  • Centro Nacional de Investigaciones Cardiovasculares Carlos III CNIC, Madrid, Spain, Madrid, Spain

  • University Hospital Basel, Basel, Switzerland

  • Gustave Roussy Cancer Campus, Villejuif, France

  • University of Oviedo, Oviedo, Spain

  • Oxford University, Oxford, United Kingdom

Locations

  • United Kingdom

  • Spain

  • Switzerland

  • France

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Genetic Disorder

Disease

  • Myeloid neoplasms

  • Myelofibrosis

  • Hutchinson-Gilford progeria syndrome

Biomarkers

  • Cluster of Differentiation 34

  • Interleukin 6

Drug/Treatment

  • Nitric oxide

  • CXCL12

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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