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: RNA-Seq Analysis of Clonal Hematopoiesis (CHIP) Blood Leukocytes Shows Dysregulation of Neutrophil / Innate Immunity-Related Genes

Researchers

Presenter

  • Elina K Cook

Principal Investigators

  • Richard N Armstrong

  • Eshita Sharma

  • Brooke Snetsinger

  • Jacqueline Boultwood

  • Rena Buckstein

  • Andrea Pellagatti

  • Michael J. Rauh

Medical Centers

  • Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada

  • Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford and Haematology Theme Oxford Biomedical Research Centre, Oxford, United Kingdom

  • The Wellcome Trust Centre For Human Genetics, University of Oxford, Oxford, United Kingdom

  • Odette Cancer Center, Sunnybrook Health Sciences Centre, Toronto, ON, Canada

Locations

  • Canada

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Myeloid neoplasms

  • Myelodysplastic Syndrome

Biomarkers

  • Myeloperoxidase

  • DNA methyltransferase 3 alpha

  • Lactotransferrin

  • Tet methylcytosine dioxygenase 2

  • Splicing Factor 3b Subunit 1

Drug/Treatment

  • N/A

Outcome

  • N/A


Study Design

  • Cohort

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A