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: Therapy-Related Myeloid Neoplasms with Balanced Chromosome Rearrangements Frequently Arise from Pre-Existing Clonal Haematopoiesis

Researchers

Presenter

  • Richard Dillon

Principal Investigators

  • Jelena Jovanovic

  • Nicola Potter

  • Nicola Foot

  • Matthew J Ahearne

  • Sandrine Jayne

  • Michael Dennis

  • Ann E. Hunter

  • Martin J.S. Dyer

  • Paresh Vyas

  • Lynn Quek

  • Nigel H. Russell

  • Robert K. Hills

  • Ellen Solomon

  • David Grimwade

Medical Centers

  • Kings College London, London, United Kingdom

  • Molecular Oncology Diagnostics Unit, ViaPath LLP, London, United Kingdom

  • Department of Oncology, University of Leicester, Leicester, United Kingdom

  • University of Leicester, Ernest and Helen Scott Haematological Research Institute, Leicester, United Kingdom

  • Department of Haematology and Transplant, The Christie, Manchester, United Kingdom

  • Leicester Royal Infirmary, Leicester, UK

  • The Ernest and Helen Scott Haematological Research Institute, University Hospitals of Leicester NHS Trust, Leicester, United Kingdom

  • IGF Group, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom

  • IGF Group, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom

  • Nottingham City Hospital, Nottingham, United Kingdom

  • Centre for Trials Research, College of Biomedical & Life Sciences, Cardiff University, Cardiff, United Kingdom

  • King's College London, Faculty of Life Sciences and Medicine, London, United Kingdom

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute promyelocytic leukemia

  • Myeloid neoplasms

  • Hodgkin's Lymphoma

  • T-cell lymphoma

  • Solid malignancies

  • Lymphomas

Biomarkers

  • MYCN proto-oncogene, bHLH transcription factor

  • Cluster of Differentiation 34

  • DNA methyltransferase 3 alpha

  • Tumor protein p53

  • Splicing Factor 3b Subunit 1

Drug/Treatment

  • arsenic

  • T-15

  • TP53

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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