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: Serum Proteomics Reveals Distinct Subtypes Associated with Treatment Response in Idiopathic Multicentric Castleman Disease

Researchers

Presenter

  • Dustin Shilling

Principal Investigators

  • Christopher Sheild Nabel

  • Sheila K Pierson

  • Mary Guilfoyle

  • Craig Tendler

  • Manjula P Reddy

  • Michael Weinblatt

  • Nancy Shadick

  • Mark Bower

  • Alessia Dalla Pria

  • Yasufumi Masaki

  • Philip Beineke

  • Sofija Miljovska

  • Laura Katz

  • Sushila Shenoy

  • Ana B Oromendia

  • Jason Mezey

  • Jeff Wiser

  • Jef Benbanaste

  • David Lee

  • Alexander Foss

  • Frits van Rhee

  • David C Fajgenbaum

Medical Centers

  • Castleman Disease Collaborative Network, Philadelphia, PA

  • University of Pennsylvania, Philadelphia, PA

  • Castleman Disease Collaborative Network, Boston, MA

  • Janssen Pharmaceuticals, Raritan, NJ

  • Johnson & Johnson, Spring House, PA

  • Brigham and Women's Hospital, Brookline, MA

  • Chelsea and Westminster Hospital, London, United Kingdom

  • Department of Hematology and Immunology, Kanazawa Medical University, Uchinada, Japan

  • Medidata Solutions, Inc., New York, NY

  • Dept of Medicine, Weill Cornell Medicine, New York, NY

  • Department of Biological Statistics and Computational Biology, Cornell University, Ithica, NY

  • Oslo University Hospital, Oslo, Norway

  • University of Arkansas for Medical Sciences, Little Rock, AR

Locations

  • United States

  • United Kingdom

  • Japan

  • Norway

Companies

  • Medidata Solutions,

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Infectious Diseases (ID)

  • Genetic Disorder

  • Autoimmune (AI)

Disease

  • Systemic inflammation

  • Rheumatoid arthritis

  • Kaposi's sarcoma

  • Castleman disease

  • Hodgkin's Lymphoma

  • Inflammatory Arthritis

  • Lymphomas

  • Idiopathic multicentric Castleman’ s disease

Biomarkers

  • Cancer antigen 15-3

  • Human albumin

Drug/Treatment

  • ILS-969

  • Siltuximab

Outcome

  • N/A

Study Design

  • Multicenteric

Phase

  • II

Study Id's

  • NCT01024036

Sponsors

  • N/A

Result

  • N/A

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