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: GDF15 and Erythroferrone Mark Erythropoietic Response to ACE-011 (Sotatercept) in Thalassemia

Researchers

Presenter

  • Maciej W Garbowski

Principal Investigators

  • Maria Domenica Cappellini

  • Raffaella Origa

  • Gian Luca Forni

  • Ersi Voskaridou

  • Frdric Galactros

  • Ali Taher

  • Jean Benot Arlet

  • Jean-Antoine Ribeil

  • Giovanna Graziadei

  • Chantal Brouzes

  • Michaela Semeraro

  • Patricia Evans

  • Abderrahmane Laadem

  • Dimana Miteva

  • Jun Zou

  • Tatiana Zinger

  • Martin Schwickart

  • Victoria Sung

  • John Porter

Medical Centers

  • Research Haematology Department, University College London, London, United Kingdom

  • Department of Medical Oncology, University College London Hospital, London, United Kingdom

  • Clinical Hematology, Necker University Hospital, Paris, France

  • Foundation IRCCS Ca' Granda Policlinico Milano - University of Milan, Milano, MI, Italy

  • Ospedale Pediatrico Microcitemico atA.Ca-, University of Cagliari, Cagliari, Italy

  • Hematology - Thalassemia and Congenital Anemia Center, Ospedale Galliera, Genova, Italy

  • Thalassemia and Sickle Cell Disease Center, Laikon University General Hospital, Athens, Greece

  • UMGGR, 6UMGGR, Hôpital Henri Mondor; Assistance Publique-Hôpitaux de Paris (APHP); UPEC,, Créteil, France

  • Department of Pediatrics and Adolescent Medicine, American University of Beirut Medical Center, Beirut, Lebanon

  • Georges-Pompidou European Hospital - APHP, Paris, France

  • Biotherapy Department, APHP Necker, Paris, France

  • UOS Medical Genetics Laboratory. Fond. IRCCS Ca Granda, Ospedale Maggiore Policlinico, Milan, Italy

  • laboratoire d'Hematologie, Hôpital Universitaier Necker Enfants Malades, Paris, France

  • Laboratory of Onco-Hematology, Hopital Necker Enfants-Malades, APHP, Paris, France

  • Celgene Corporation, Summit, NJ

  • Celgene Corporation, Boudry, Switzerland

  • Celgene Corporation, San Francisco, CA

Locations

  • United Kingdom

  • France

  • Italy

  • Greece

  • Lebanon

  • United States

  • Switzerland

Companies

  • Celgene Corporation

Study Components

Therapeutic Area

  • Blood/haematological Diseases

Disease

  • Thalassemia

  • Non‐transfusion‐dependent β‐thalassaemia

Biomarkers

  • Growth differentiation factor 15

  • Tumor doubling time

Drug/Treatment

  • Sotatercept

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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