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430 : PLUTO: A randomised phase II study of pazopanib versus paclitaxel in relapsed urothelial tumours.

Researchers

Presenter

  • Thomas Powles

Principal Investigators

  • Andrew Protheroe

  • Alison Birtle

  • Prabir R Chakraborti

  • Robert Huddart

  • Satinder Jagdev

  • Amit Bahl

  • Andrew Stockdale

  • Santhanam Sundar

  • Simon J. Crabb

  • Judith Dixon-Hughes

  • Laura Alexander

  • Caroline A Bray

  • Jamie Stobo

  • Akhila Ganeshi Wimalasingham

  • Charlotte Ackerman

  • James Paul

  • Rob Jones

Medical Centers

  • Barts Cancer Institute, Barts Health, and The Royal Free London NHS Foundation Trust, London, United Kingdom

  • University of Liverpool, Clatterbridge Cancer Centre NHS Foundation Trust, Wirral, United Kingdom

  • Churchill Hospital, Oxford Medical Oncology Department, Oxford, United Kingdom

  • Royal Lancaster Infirmary, Lancaster, United Kingdom

  • Royal Derby Hospital, Derby, United Kingdom

  • The Institute of Cancer Research, The Royal Marsden NHS Foundation Trust, Sutton, United Kingdom

  • St. James's University Hospital, Leeds, United Kingdom

  • University Hospitals Bristol NHS Foundation Trust - Bristol Haematology and Oncology Centre, Department of Oncology, Bristol, United Kingdom

  • Arden Cancer Centre, University Hospital, Coventry, United Kingdom

  • Nottingham University Hospitals NHS Trust - City Hospital, Consultant Medical Oncologist, Nottingham, United Kingdom

  • University of Southampton, Southampten, United Kingdom

  • Cancer Research UK Clinical Trials Unit, University of Glasgow, Glasgow, United Kingdom

  • Guy's Hospital, London, United Kingdom

  • Bart's Cancer Institute, London, United Kingdom

  • University of Liverpool, Liverpool, United Kingdom

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Solid malignancies

Biomarkers

  • Ribosomal Protein S27a

Drug/Treatment

  • Paclitaxel

  • Pazopanib

Outcome

  • N/A


Study Design

  • Randomized

Phase

  • II

Study Id's

  • NCT00949455

Sponsors

  • N/A

Result

  • N/A