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ABS089 : EFFICACY AND SAFETY OF ETRANACOGENE DEZAPARVOVEC IN ADULTS WITH SEVERE OR MODERATE‐SEVERE HEMOPHILIA B: FIRST DATA FROM THE PHASE 3 HOPE‐B GENE THERAPY TRIAL

Researchers

Presenter

  • S. W Pipe

Principal Investigators

  • N. S Key

  • F. WG Leebeek

  • G. Castaman

  • S. U Lattimore

  • P. van der Valk

  • K. Peerlinck

  • M. Coppens

  • N. OConnell

  • K. J. Pasi

  • P. Kampmann

  • K. Meijer

  • A. von Drygalski

  • G. Young

  • C. Hermans

  • J. Astermark

  • R. Klamroth

  • R. S Lemons

  • N. Visweshwar

  • S. Crary

  • R. Kazmi

  • E. Symington

  • M. A Escobar

  • E. Gomez

  • R. Kruse-Jarres

  • A. Kotowski

  • D. Quon

  • M. Wang

  • A. P Wheeler

  • E. K Sawyer

  • S. Verweij

  • V. Colletta

  • N. Bajwa

  • R. Gut

  • W. Miesbach

Medical Centers

  • University of Michigan, Ann Arbor, MI

  • Oregon Health and Science University, Portland, OR

  • Department of Epidemiology, University of North Carolina, Chapel Hill, NC, United States

  • Erasmus University Medical Center, Rotterdam, Netherlands

  • Azienda Ospedaliero-Universitaria Careggi, Florence, Italy

  • Hematology and Van Creveld Cinic, University Medical Center Utrecht, Utrecht, Netherlands

  • Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands

  • Saint James's Hospital, Dublin, Ireland

  • Royal London Haemophilia Centre, Barts and the London School of Medicine and Dentistry, London, United Kingdom

  • Rigshospitalet, Copenhagen, Denmark

  • Universitair Medisch Centrum Groningen, Groningen, Netherlands

  • University of California, San Diego, La Jolla, CA

  • Children's Hospital, Los Angeles, CA, United States

  • Cliniques Universitaires Saint-Luc, Universite Catholique de Louvain, Brussels, Belgium

  • Lund University Hospital, Lund, Sweden

  • Vivantes Klinikum Am Friedrichshain, Berlin, Germany

  • University of Utah, Salt Lake City, UT

  • University of South Florida, Tampa, FL

  • University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States

  • University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom

  • Cambridge University Hospitals, Cambridge, United Kingdom

  • The University of Texas Health Science Center at Houston, Houston, TX

  • Phoenix Children's Hospital, Phoenix, AZ

  • Bloodworks Northwest, Seattle, WA

  • Hemophilia Center of Western New York, New York

  • Los Angeles Orthopedic Hospital, Orthopedic Hemophilia Treatment Center, Los Angeles, United States

  • Anschutz Medical Campus, University of Colorado Denver, Aurora, CO

  • Vanderbilt University Medical Center, Nashville, TN

  • Shire, Lexington, United States

  • University Hospital Frankfurt, Frankfurt, Germany

Locations

  • United States

  • Netherlands

  • Italy

  • Belgium

  • Ireland

  • United Kingdom

  • Denmark

  • Sweden

  • Germany

Companies

  • N/A

Study Components

Therapeutic Area

  • Blood/haematological Diseases

Disease

  • Hemophilia

Biomarkers

  • N/A

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • Multinational

Phase

  • III

Study Id's

  • NCT03569891

Sponsors

  • N/A

Result

  • N/A

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