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OC5.4 : Drug repurposing identifies inhibitors of the proteostasis network to augment radioiodine uptake in combinatorial approaches targeting thyroid cancer

Researchers

Presenter

  • Martin Read

Principal Investigators

  • Katie Brookes

  • Alice Fletcher

  • Caitlin Thornton

  • Mohammed Alshahrani

  • Rashida Khan

  • Hannah Nieto

  • Holly Adcock

  • Jamie Webster

  • Liam Cox

  • Luke Alderwick

  • Kristien Boelaert

  • Vicki Smith

  • Christopher McCabe

Medical Centers

  • University of Birmingham, Institute of Metabolism and Systems Research, Birmingham, United Kingdom

  • The University of Birmingham, School of Cancer Sciences, Birmingham, United Kingdom

  • University of Birmingham, Protein Expression Facility, College of Medical and Dental Sciences, Birmingham, United Kingdom

  • University of Birmingham, Institute of Microbiology and Infection, School of Biosciences, Birmingham, United Kingdom

  • University of Birmingham, Institute of Applied Health Research, United Kingdom

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Endocrine/metabolic Diseases (ME)

Disease

  • Thyroid Cancer

Biomarkers

  • N/A

Drug/Treatment

  • Sodium Iodide

  • Clotrimazole

  • Vorinostat

  • Ebastine

  • TPC-1

  • DMSO

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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