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1236 : Establishing a Th2 and Tfh cell exhaustion in vitro model using TCR Signaling to test T cell anergy during immunotherapy

Researchers

Presenter

  • Zhu R

Principal Investigators

  • Sharif H

  • Laisuan W

  • Layhadi JA

  • Oleksandra F

  • Liu Z

  • Durham SR

  • Shamji MH

Medical Centers

  • Immunomodulation and Tolerance Group, Allergy and Clinical Immunology, Department of National Heart and Lung Institute, Imperial College London, London, United Kingdom

  • NIHR Biomedical Research Centre, Asthma UK Centre in Allergic Mechanisms of Asthma, London, Imperial College London, London, United Kingdom

  • Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

  • Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

Locations

  • United Kingdom

  • China

Companies

  • N/A

Study Components

Therapeutic Area

  • Autoimmune (AI)

  • Infectious Diseases (ID)

Disease

  • Allergic rhinitis

Biomarkers

  • Cluster of Differentiation 2AP

  • Cluster of Differentiation 4

  • T-cell receptor

  • T helper 2

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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