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497 : Bipotent Lymphoid Progenitors Independently Maintain Long-Term Genetically Engineered T and NK Cell Production in Humans

Researchers

Presenter

  • Natalia Izotova

Principal Investigators

  • Christine Rivat

  • Cristina Baricordi

  • Elena Blanco-Alvarez

  • Danilo Pellin

  • Eleanor Watt

  • Soragia Athina Gkazi

  • Stuart Adams

  • Kimberly Gilmour

  • Jinhua Xu Bayford

  • Claire Booth

  • Bobby H Gaspar

  • Adrian J. Thrasher

  • Luca Biasco

Medical Centers

  • Great Ormond Street Institute of Child Health, UCL, London, United Kingdom

  • Dana Farber Boston Childrens Cancer and Blood Disorder Center, Harvard Medical School, Boston, MA

  • Great Ormond Street Hospital, London, United Kingdom

Locations

  • United Kingdom

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Solid malignancies

Biomarkers

  • Natural Killer cells

  • Cluster of differentiation 95

  • Protein Tyrosine Phosphatase, Receptor Type C

  • Cyclin D2

  • LIM Domain Only 2

  • L-selectin

  • MDS1 And EVI1 Complex Locus

  • T-cell receptor

Drug/Treatment

  • IFN-lambda

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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