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451 : Enhanced Free Fatty Acid Uptake Via CD36 Promotes a Metabolic Switch to B-Oxidation within Hematopoietic Stem Cells in Response to Acute Infection

Researchers

Presenter

  • Jayna J Mistry

Principal Investigators

  • Jamie A Moore

  • Charlotte Hellmich

  • Aisha Jibril

  • Iain Macauley

  • Mar Moreno-Gonzalez

  • Federica Di Palma

  • Naiara Beraza

  • Kristian M Bowles

  • Stuart A Rushworth

Medical Centers

  • Norwich Medical School, The University of East Anglia, Attleborough, ENG, United Kingdom

  • Norwich Medical School, The University of East Anglia, Attleborough, ENG, United Kingdom

  • University of East Anglia, Norwich, UK

  • Medicine, Norwich Medical School University of East Anglia, Norwich, United Kingdom

  • Quadram Institute, UK, Coventry, United Kingdom

  • Quadram Institute, UK, Coventry, United Kingdom

  • Quadram Institute, UK, Coventry, United Kingdom

  • Ophthalmology, Norfolk & Norwich University Hospitals NHS Foundation Trust, Norwich, United Kingdom

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Central Nervous System (CNS)

  • Genetic Disorder

Disease

  • Tuberculosis

  • Spinocerebellar ataxia 1

Biomarkers

  • Cluster of Differentiation 34

  • Cluster of differentiation 45

  • KIT Proto-Oncogene, Receptor Tyrosine Kinase

Drug/Treatment

  • Etomoxir

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A