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414 : Depth of Response and Response Kinetics of Isatuximab Plus Carfilzomib and Dexamethasone in Relapsed Multiple Myeloma: Ikema Interim Analysis

Researchers

Presenter

  • Thomas Martin

Principal Investigators

  • Joseph Mikhael

  • Roman Hajek

  • Kihyun Kim

  • Kenshi Suzuki

  • Cyrille Hulin

  • Mamta Garg

  • Hang Quach

  • Hanlon Sia

  • Anup George

  • Tatiana Konstantinova

  • Marie-Laure Risse

  • Gaelle Asset

  • Sandrine Mac

  • Helgi van de Velde

  • Philippe Moreau

Medical Centers

  • Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA

  • Translational Genomics Research Institute, City of Hope Cancer Center, Phoenix, AZ

  • Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic

  • Division of Hematology and Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea

  • Department of Surgical Oncology, Japanese Red Cross Medical Center, Tokyo, Japan

  • Department of Haematology, University Hospital of Bordeaux, Bordeaux, France

  • Department of Haematology, Leicester Royal Infirmary, University Hospitals of Leicester NHS Trust, Leicester, United Kingdom

  • Department of Haematology, St Vincent's Hospital, Darlinghurst, Australia

  • Cancer Care & Haematology Unit, The Tweed Hospital, Tweed Heads, NSW, Australia

  • Wellington Blood and Cancer Center, Wellington, New Zealand

  • Hematology Department, Regional Clinical Hospital №1, Ekaterinburg, Russian Federation

  • Sanofi Research and Development, Vitry-Sur-Seine, France

  • Sanofi, Chilly-Mazarin, France

  • Sanofi, Cambridge, MA

  • Department of Hematology, CHU Nantes, Nantes, France

Locations

  • United States

  • Czech Republic

  • Republic of South Korea

  • Japan

  • France

  • United Kingdom

  • Australia

  • New Zealand

  • Russia

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Multiple Myeloma

Biomarkers

  • N/A

Drug/Treatment

  • Dexamethasone

  • Dekpak 13 Day Taperpak

  • carfilzomib Intravenous

  • Isatuximab

Outcome

  • N/A

Study Design

  • Randomized

  • Open Label

  • Multicenteric

Phase

  • III

Study Id's

  • NCT03275285

Sponsors

  • N/A

Result

  • N/A

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