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2433 : Local and Systemic Effects of Immune Checkpoint Blockade on Relapsed Myeloid Malignancies Following Allogeneic Hematopoietic Stem Cell Transplantation

Researchers

Presenter

  • Livius Penter

Principal Investigators

  • Alexandra Savell

  • Srinika Ranasinghe

  • Teddy Huang

  • Nicoletta Cieri

  • Satyen H Gohil

  • Wandi Zhang

  • Shuqiang Li

  • Robert Zeiser

  • Haesook T. Kim

  • Kenneth J. Livak

  • Jerome Ritz

  • Donna S. Neuberg

  • Robert J. Soiffer

  • X. Shirley Liu

  • Matthew S. Davids

  • Pavan Bachireddy

  • Catherine J. Wu

Medical Centers

  • Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA

  • Department of Hematology, Oncology, and Tumor Immunology, Charité-Universitätsmedizin Berlin,Berlin,Allemagne

  • Harvard Medical School, Boston, MA

  • Broad Institute of MIT and Harvard, Cambridge, MA

  • Department of Imaging, Dana-Farber Cancer Institute, Boston, MA

  • Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA

  • Center for Neuro-Oncology at Dana-Farber Cancer Institute, Boston, MA

  • Translational Immunogenomics Lab, Dana-Farber Cancer Institute, Boston, MA

  • Department of Haematology, University College London Cancer Institute,London,United Kingdom

  • Medical Faculty University of Freiburg, Freiburg Im Breisgau, GA, Germany

  • Department of Medicine, Brigham and Women's Hospital, Boston, MA

  • Department of Medicine, Brigham and Women's Hospital, Boston, MA

Locations

  • United States

  • Germany

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Autoimmune (AI)

Disease

  • Graft-versus-host disease

Biomarkers

  • Cluster of Differentiation 4

  • Programmed death-ligand 1

  • Cluster of differentiation 8A

  • Human Leukocyte Antigen – DR isotype

  • Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Epsilon

  • T-cell receptor

Drug/Treatment

  • Ipilimumab

  • Nivolumab

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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